Psoriasis is a complex immune-mediated inflammatory skin disease characterized by T-cell-
driven epidermal hyperplasia. It occurs on a strong genetic predisposition. The human …

Psoriasis is a chronic disease that affects the skin and joints. Clinical hallmarks comprise
erythematous plaques covered by silvery scaling and a chronic recurrent course …

Psoriasis is a chronic, inflammatory, immune-mediated skin condition with a prevalence of 0–
11.8% across the world. It is associated with a number of cardiovascular, metabolic, and …

Psoriasis is a chronic inflammatory skin disease with a clear genetic contribution,
characterized by keratinocyte proliferation and immune cell infiltration. Various closely …

VOL. 102 NO. 5S I NOVEMBER 2018 7 WWW. MDEDGE. COM/CUTIS region. Current
research on the pathogenesis of psoriasis examines the complex interactions among …

The pro-inflammatory cytokine interleukin-1 (IL-1) is constitutively expressed by
keratinocytes in vivo and has been shown to be expressed in psoriatic lesional skin. To …

Over the last decade, the management of psoriasis has witnessed a paradigm shift. Thanks
to the increasing knowledge about the pathogenesis of psoriasis, targeted treatments with …

Psoriasis is a disease involving the innate and adaptative components of the immune
system, and it is triggered by environmental factors in genetically susceptible individuals …

Psoriasis is a chronic autoimmune disease with complex genetic architecture. Previous
genome-wide association studies (GWAS) and a recent meta-analysis using Immunochip …

Psoriasis is a complex, chronic relapsing and inflammatory skin disorder with a prevalence
of approximately 2% in the general population worldwide. Psoriasis can be triggered by …