Abstract Activation of Sirtuin1 (Sirt1), an nicotinamide adenine dinucleotide oxidized-
dependent deacetylase, by natural or synthetic compounds like resveratrol, SRT2104, or …

Mitochondria are the powerhouse of eukaryotic cells, which regulate cell metabolism and
differentiation. Recently, mitochondrial transfer between cells has been shown to direct …

This study aimed to probe into the effect of TRIM33 on oxidative stress‐induced apoptosis of
osteoblasts in osteoporosis and to probe into the underlying mechanism. The apoptosis of …

Background The osteogenic differentiation ability of adipose-derived stem cells (ASCs) is
attenuated in type 2 diabetic osteoporosis (Dop) mice. Several studies suggest autophagy …

Administration of glucocorticoids is an effective strategy for treating many inflammatory and
autoimmune diseases. However, glucocorticoid treatment can have adverse effects on bone …

Maintenance of a healthy proteome is essential for cellular homeostasis and loss of
proteostasis is associated with tissue dysfunction and neurodegenerative disease. The …

Reorganization of the podosome into the sealing zone is crucial for osteoclasts (OCLs) to
resorb bone, but the underlying mechanisms are unclear. Here, we show that tuberous …

Autophagy is an evolutionarily conserved dynamic process and present in variety of cells at
basal levels to maintain homeostasis and to promote cell survival in response to stresses …

Abstract Resveratrol (3, 5, 4-trihydroxystilbene, RES), a natural antioxidant, prevents bone
loss by attenuating damage caused by oxidative stress. Our previous research revealed that …

Osteoblasts have recently been found to play a role in regulating glucose metabolism
through secretion of osteocalcin. It is unknown, however, how this osteoblast function is …