The anti-cancer effects of metformin, the most widely used drug for type 2 diabetes, alone or
in combination with ionizing radiation were studied with MCF-7 human breast cancer cells …

Background: Nowadays, ionizing radiation is used for several applications in medicine,
industry, agriculture, and nuclear power generation. Besides the beneficial roles of ionizing …

Over the last decade, evidence has emerged to support a role for the antidiabetic drug
metformin in the prevention and treatment of cancer. In particular, recent studies …

Metformin, the most widely prescribed drug for treatment of type 2 diabetes, has been shown
to exert significant anticancer effects. Hyperthermia has been known to kill cancer cells and …

Pancreatic cancer is relatively radioresistant, however, radiotherapy has been shown to
provide efficacy in the treatment of local disease. To increase the effectiveness of …

Background: We examined the potential of metformin (MET) to enhance non-small cell lung
cancer (NSCLC) responses to ionising radiation (IR). Methods: Human NSCLC cells, mouse …

Cisplatin is an extensively used chemotherapeutic drug for lung cancer, but the
development of resistance decreases its effectiveness in the treatments of non-small cell …

Metformin, a first line medication for type II diabetes, initially entered the spotlight as a
promising anti-cancer agent due to epidemiologic reports that found reduced cancer risk …

Metformin is widely used in the treatment of diabetes mellitus type 2 where it reduces insulin
resistance and diabetes-related morbidity and mortality. Population-based studies show that …

The biguanide metformin, a widely used drug for the treatment of type 2 diabetes, may exert
cancer chemopreventive effects by suppressing the transformative and hyperproliferative …