Serum and plasma proteomics
HJ Issaq, Z Xiao, TD Veenstra - Chemical reviews, 2007 - ACS Publications
There is a saying,“Eyes are the windows to the soul”. In much the same vein, blood, since it
flows through the entire body, can be considered the window to the physical condition of the …
flows through the entire body, can be considered the window to the physical condition of the …
Utilizing human blood plasma for proteomic biomarker discovery
Candidate proteomic biomarker discovery from human plasma holds both incredible clinical
potential as well as significant challenges. The dynamic range of proteins within plasma is …
potential as well as significant challenges. The dynamic range of proteins within plasma is …
Recent advances in blood‐related proteomics
L Thadikkaran, MA Siegenthaler, D Crettaz… - …, 2005 - Wiley Online Library
Blood is divided in two compartments, namely, plasma and cells. The latter contain red
blood cells, leukocytes, and platelets. From a descriptive medical discipline, hematology has …
blood cells, leukocytes, and platelets. From a descriptive medical discipline, hematology has …
Opportunities for sensitive plasma proteome analysis
U Landegren, J Vänelid, M Hammond… - Analytical …, 2012 - ACS Publications
Despite great interest, investments, and efforts, the ongoing search for plasma protein
biomarkers for disease so far has come up surprisingly empty-handed. Although discovery …
biomarkers for disease so far has come up surprisingly empty-handed. Although discovery …
Mass spectrometry-based plasma proteomics: considerations from sample collection to achieving translational data
The proteomic analysis of human blood and blood-derived products (eg, plasma) offers an
attractive avenue to translate research progress from the laboratory into the clinic. However …
attractive avenue to translate research progress from the laboratory into the clinic. However …
Proteomics: the next revolution in laboratory medicine?
M Plebani - Clinica chimica acta, 2005 - Elsevier
BACKGROUND: The identification of specific genetic alterations and protein profiles
associated with disease offers a unique opportunity to develop proteomics-based assays for …
associated with disease offers a unique opportunity to develop proteomics-based assays for …
Mass spectrometry-based plasma proteomics: state of the art and future outlook
M Pernemalm, J Lehtiö - Expert review of proteomics, 2014 - Taylor & Francis
Mass spectrometry-based plasma proteomics is a field where intense research has been
performed during the last decade. Being closely linked to biomarker discovery, the field has …
performed during the last decade. Being closely linked to biomarker discovery, the field has …
Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry
Blood serum is a complex body fluid that contains various proteins ranging in concentration
over at least 9 orders of magnitude. Using a combination of mass spectrometry technologies …
over at least 9 orders of magnitude. Using a combination of mass spectrometry technologies …
Proteomics from the clinical perspective: many hopes and much debate
L Beretta - Nature Methods, 2007 - nature.com
Proteomics from the clinical perspective: many hopes and much debate | Nature Methods Skip
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to main content Thank you for visiting nature.com. You are using a browser version with limited …
Blood-related proteomics
G Liumbruno, A D'Alessandro, G Grazzini, L Zolla - Journal of proteomics, 2010 - Elsevier
Blood-related proteomics is an emerging field, recently gaining momentum. Indeed, a wealth
of data is now available and a plethora of groups has contributed to add pieces to the jigsaw …
of data is now available and a plethora of groups has contributed to add pieces to the jigsaw …