[HTML][HTML] Impaired expression of GABA signaling components in the Alzheimer's disease middle temporal gyrus
K Govindpani, C Turner, HJ Waldvogel… - International journal of …, 2020 - mdpi.com
γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter, playing a central role
in the regulation of cortical excitability and the maintenance of the excitatory/inhibitory (E/I) …
in the regulation of cortical excitability and the maintenance of the excitatory/inhibitory (E/I) …
[HTML][HTML] Gamma-aminobutyric acid A receptors in Alzheimer's disease: highly localized remodeling of a complex and diverse signaling pathway
A Kwakowsky, BCF Guzmán… - Neural regeneration …, 2018 - journals.lww.com
Conclusions: Our findings demonstrated that the GABAergic system suffers significant
remodeling in the brains of AD patients, yet it is to be determined if this is as a consequence …
remodeling in the brains of AD patients, yet it is to be determined if this is as a consequence …
Impaired expression of GABA transporters in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus
TE Fuhrer, TH Palpagama, HJ Waldvogel, BJL Synek… - Neuroscience, 2017 - Elsevier
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain and
plays an important role in regulating neuronal excitability. GABA reuptake from the synapse …
plays an important role in regulating neuronal excitability. GABA reuptake from the synapse …
[HTML][HTML] Towards a better understanding of GABAergic remodeling in Alzheimer's disease
K Govindpani, B Calvo-Flores Guzmán… - International journal of …, 2017 - mdpi.com
γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the vertebrate brain.
In the past, there has been a major research drive focused on the dysfunction of the …
In the past, there has been a major research drive focused on the dysfunction of the …
GABAA receptor subunit expression changes in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus
A Kwakowsky, B Calvo‐Flores Guzmán… - Journal of …, 2018 - Wiley Online Library
Gamma‐aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central
nervous system. GABA type A receptors (GABAAR s) are severely affected in Alzheimer's …
nervous system. GABA type A receptors (GABAAR s) are severely affected in Alzheimer's …
Factors affecting the GABAergic synapse function in Alzheimer's disease: Focus on microRNAs
Alzheimer's disease (AD) is a progressive neurological disease characterized by the loss of
cognitive function, confusion, and memory deficit. Accumulation of abnormal proteins …
cognitive function, confusion, and memory deficit. Accumulation of abnormal proteins …
Loss of functional GABAA receptors in the Alzheimer diseased brain
A Limon, JM Reyes-Ruiz… - Proceedings of the …, 2012 - National Acad Sciences
The cholinergic and glutamatergic neurotransmission systems are known to be severely
disrupted in Alzheimer's disease (AD). GABAergic neurotransmission, in contrast, is …
disrupted in Alzheimer's disease (AD). GABAergic neurotransmission, in contrast, is …
The GABAergic system in Alzheimer's disease: a systematic review with meta-analysis
G Carello-Collar, B Bellaver, PCL Ferreira… - Molecular …, 2023 - nature.com
The γ-aminobutyric acid (GABA) ergic system is the primary inhibitory neurotransmission
system in the mammalian brain. Its dysregulation has been shown in multiple brain …
system in the mammalian brain. Its dysregulation has been shown in multiple brain …
The GABAergic system as a therapeutic target for Alzheimer's disease
B Calvo‐Flores Guzmán, C Vinnakota… - Journal of …, 2018 - Wiley Online Library
Glutamatergic and cholinergic dysfunction are well‐attested features of Alzheimer's disease
(AD), progressing with other pathological indices of the disorder and exacerbating neuronal …
(AD), progressing with other pathological indices of the disorder and exacerbating neuronal …
Subregional analysis of GABAA receptor subunit mRNAs in the hippocampus of older persons with and without cognitive impairment
RA Rissman, DA Bennett, DM Armstrong - Journal of chemical …, 2004 - Elsevier
We employed in situ hybridization and quantitative densitometry techniques to examine
hippocampal mRNA expression of GABAA receptor subunits α1 and α5 in human subjects …
hippocampal mRNA expression of GABAA receptor subunits α1 and α5 in human subjects …
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