We employed in situ hybridization and quantitative densitometry techniques to examine
hippocampal mRNA expression of GABAA receptor subunits α1 and α5 in human subjects …

In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic)
system in age-related episodic memory impairments in humans, with a particular focus on …

Our work on the role of glutamate in Alzheimer's disease (AD)-related neuronal vulnerability
and death provided significant insight into the potential contribution of the γ-aminobutyric …

Background: The early phase of Alzheimer's disease (AD) involves the disruption of finely
tuned neuronal circuitry in brain regions associated with learning and memory. This tuning is …

Alterations in neurotransmitter homeostasis, primarily of glutamate and GABA, is strongly
implicated in the pathophysiology of Alzheimer's disease (AD). Homeostasis at the synapse …

Alzheimer's disease (AD) is characterized by selective vulnerability of specific neuronal
populations within particular brain regions. For example, hippocampal glutamatergic cell …

Alterations in the γ-aminobutyric acid (GABA) neurotransmitter and receptor systems may
contribute to vulnerability of hippocampal pyramidal neurons in Alzheimer's disease (AD) …

Alzheimer's disease (AD) is characterized pathologically by the deposition of β-amyloid
peptides (Aβ) and the accumulation of neurofibrillary tangles (NFTs) composed of hyper …

The imbalance between glutamate and γ‐aminobutyric acid (GABA) results in the loss of
synaptic strength leading to neurodegeneration. The dogma on the field considered neurons …

Metabotropic γ-aminobutyric acid (GABAB) receptors contribute to the control of network
activity and information processing in hippocampal circuits by regulating neuronal …