Astrocytes are glial cells that are distributed throughout the central nervous system in an
arrangement optimal for chemical and physical interaction with neuronal synapses and …

Gamma aminobutyric acid (GABA) B receptors (GABABRs) have been linked to a wide
range of physiological and cognitive processes and are of interest for treating a number of …

Alzheimer's disease (AD) is an unremitting neurodegenerative disorder characterized by
cerebral amyloid-β (Aβ) accumulation and gradual decline in cognitive function. Changes in …

Synaptic inhibition in the mammalian central nervous system is mostly mediated by GABA (γ-
aminobutyric acid). Inhibitory interneurons can be identified by staining for glutamate …

GABA uptake limits GABA actions during synaptic responses when the density of active
release sites is high or multiple axons are synchronously activated. GABA transporter-1 …

Tonic GABA type A (GABAA) conductance is a key factor regulating neuronal excitability and
computation in neuronal networks. The magnitude of the tonic GABAA conductance …

Aging is associated with reduced brain volume, altered neural activity, and neuronal atrophy
in cortical-like structures, comprising the frontal cortex and hippocampus, together …

A cDNA clone encoding a human γ‐aminobutyric acid (GABA) transporter has been isolated
from a brain cDNA library, and its functional properties have been examined in mammalian …

Astrocytes play critical roles in central nervous system homeostasis and support of neuronal
function. A better knowledge of their response may both help understand the …

Alzheimer's disease (AD) is the leading type of dementia worldwide. Despite an increasing
burden of disease due to a rapidly aging population, there is still a lack of complete …