Background Francisella tularensis causes severe pulmonary disease, and nasal vaccination
could be the ideal measure to effectively prevent it. Nevertheless, the efficacy of this type of …

Francisella tularensis is a highly infectious intracellular bacterium that causes the zoonotic
infection tularemia. While much literature exists on the host response to F. tularensis …

In the last decade several new vaccines against Francisella tularensis, which causes
tularemia, have been characterized in animal models. Whereas many of these vaccine …

The highly infectious bacterium Francisella tularensis is a facultative intracellular pathogen
and the causative agent of tularemia. TolC, which is an outer membrane protein involved in …

We employed Francisella tularensis live vaccine strain (LVS) to study mechanisms of
protective immunity against intracellular pathogens and, specifically, to understand …

Oral vaccination with the defined live attenuated Francisella novicida vaccine strain
U112ΔiglB has been demonstrated to induce protective immunity against pulmonary …

Francisella tularensis is the causative agent of a fatal human disease, tularemia. F.
tularensis was used in bioweapon programs in the past and is now classified as a category …

Mice immunised with lipopolysaccharide (LPS) from Francisella tularensis were protected
against challenge with the live vaccine strain (LVS). However, when similarly immunised …

Previous results have demonstrated that nonspecific protective immunity against lethal
Francisella tularensis live vaccine strain (LVS) or Listeria monocytogenes infection can be …

Francisella tularensis can cause fatal respiratory tularemia in humans and animals and is
increasingly being isolated in the United States and several European countries. The …