Central nervous system (CNS) tumors are the most common solid tumor in pediatrics,
accounting for approximately 25% of all childhood cancers, and the second most common …

Brain tumors collectively represent the most common solid tumors in childhood and account
for significant morbidity and mortality. Until recently, pediatric brain tumors were diagnosed …

Pediatric neuro-oncology has undergone an exciting and dramatic transformation during the
past 5 years. This article summarizes data from collaborative group and institutional trials …

Abstract Purpose of Review: Pediatric brain tumors differ from those arising in adulthood.
This article discusses the presentation, location, histology, new molecular understanding …

Great progress has been made in many areas of pediatric oncology. However, tumors of the
central nervous system (CNS) remain a significant challenge. A recent explosion of data has …

High-throughput genomic technologies have shed light on the biologic heterogeneity of
several pediatric brain tumors. The biology of the four common pediatric brain tumors …

Primary brain tumors account for~ 1% of new cancer cases and~ 2% of cancer deaths in the
United States; however, they are the most commonly occurring solid tumors in children …

In recent years, brain tumors have become the single most frequent cause of cancer-related
mortality in children, although their frequency is approximately 50% less than leukemia …

Optimal integration of this newly emerging knowledge in a timely and meaningful way into
clinical care is a remarkable task and a matter of active debate. The historical morphology …

Brain tumors are the most common solid tumors in children and are associated with high
mortality. The most common childhood brain tumors are grouped as low-grade gliomas …