Background: The prolongation of spinal anesthesia by using clonidine through the oral,
intravenous and spinal route has been known. The new α2 agonist, dexmedetomidine has …

Objectives: To determine the effect of adding dexmedetomidine to bupivacaine for neuraxial
anesthesia. Methods: Sixty-six patients were studied between April and May 2008 in the …

Materials and Methods: One hundred American Society of Anesthesiologists (ASA) physical
status I/II patients undergoing elective surgeries under spinal anesthesia were randomized …

Background: We evaluated the effects of intravenous dexmedetomidine during spinal
anesthesia on hemodynamics, respiratory rate, oxygen saturation, sedpain, and compared …

Aims: Intravenous (IV) dexmedetomidine with excellent sedative properties has been shown
to reduce analgesic requirements during general anaesthesia. A study was conducted to …

Background and goals. Oral, intrathecal, and intravenous clonidine prolong bupivacaine
spinal anesthesia. There is no information on the effect of intravenous dexmedetomidine to …

Background: Alpha 2-adrenergic agonists have synergistic action with local anesthetics and
may prolong the duration of sensory, motor blockade and postoperative analgesia obtained …

Background: The supplementation of local anaesthetics with adjuvants to improve the
efficacy of subarachnoid block has been recognised since long. The most preferred drug …

Purpose Dexmedetomidine, a selective α2-adrenoceptor agonist, has analgesic and
sedative effects. The purpose of this study was to investigate the effects of small, single-dose …

Background In this prospective, randomized, double-blind, placebo-controlled trial, we tried
to find out appropriate amounts of single-dose dexmedetomidine to prolong the duration of …