[HTML][HTML] Biomarkers and key pathways in atrial fibrillation associated with mitral valve disease identified by multi-omics study

MY Li, HX Chen, HT Hou, J Wang, XC Liu… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background Mitral valve disease (MVD)-associated atrial fibrillation (AF) is one of the most
common arrhythmias with an increased risk of thromboembolic events. This study aimed to …

Role of the PPAR pathway in atrial fibrillation associated with heart valve disease: transcriptomics and proteomics in human atrial tissue

HX Chen, MY Li, YY Jiang, HT Hou, J Wang… - Signal transduction and …, 2020 - nature.com
Dear Editor, Atrial fibrillation (AF) is one of the most common cardiac arrhythmias. Its
prevalence increases significantly with age. It is well known that patients with AF are …

Comprehensive metabolomic and proteomic analyses reveal candidate biomarkers and related metabolic networks in atrial fibrillation

J Zhou, L Sun, L Chen, S Liu, L Zhong, M Cui - Metabolomics, 2019 - Springer
Introduction Atrial fibrillation (AF) is an abnormal heart rhythm characterized by an irregular
beating of the atria and is associated with an increased risk of heart failure, dementia, and …

Integration of proteomic and metabolomic characterization in atrial fibrillation-induced heart failure

H Zhang, L Wang, D Yin, Q Zhou, L Lv, Z Dong, Y Shi - BMC genomics, 2022 - Springer
Background The exact mechanism of atrial fibrillation (AF)-induced heart failure (HF)
remains unclear. Proteomics and metabolomics were integrated to in this study, as to …

Metabolomic and proteomic analyses of persistent valvular atrial fibrillation and non-valvular atrial fibrillation

B Hu, W Ge, Y Wang, X Zhang, T Li, H Cui… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) is an abnormal heart rhythm related to an increased risk of heart failure,
dementia, and stroke. The distinction between valvular and non-valvular AF remains a …

Genomic and proteomic study of the inflammatory pathway in patients with atrial fibrillation and cardiometabolic syndrome

HA Itani, MA Jaffa, J Elias, M Sabra, P Zakka… - Frontiers in …, 2020 - frontiersin.org
Atrial fibrillation (AF) and cardiometabolic syndrome (CMS) have been linked to
inflammation and fibrosis. However, it is still unknown which inflammatory cytokines …

Differences in atrial fibrillation‑associated proteins between the left and right atrial appendages from patients with rheumatic mitral valve disease: A comparative …

H Liu, G Chen, H Zheng, H Qin… - Molecular …, 2016 - spandidos-publications.com
The majority of proteomic studies have focused on identifying atrial fibrillation (AF)-
associated proteins in the right atrium (RA), thus potential differences in AF‑associated …

Using machine learning to identify proteomic and metabolomic signatures of stroke in atrial fibrillation

F Zhang, Y Zhang, Q Zhou, Y Shi, X Gao, S Zhai… - Computers in Biology …, 2024 - Elsevier
Atrial fibrillation (AF) is a common cardiac arrhythmia, with stroke being its most detrimental
comorbidity. The exact mechanism of AF related stroke (AFS) still needs to be explored. In …

Proteomic profiles of patients with atrial fibrillation provide candidate biomarkers for diagnosis

WY Zhong, H Yang, YL Wang, Y Yang, CF Guo… - International Journal of …, 2021 - Elsevier
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide with an
increasing risk of heart failure, stroke, and thromboembolic events. Currently distinct …

Integrative transcriptomic, proteomic, and machine learning approach to identifying feature genes of atrial fibrillation using atrial samples from patients with valvular …

Y Liu, F Bai, Z Tang, N Liu, Q Liu - BMC Cardiovascular Disorders, 2021 - Springer
Background Atrial fibrillation (AF) is the most common arrhythmia with poorly understood
mechanisms. We aimed to investigate the biological mechanism of AF and to discover …