Bacteriophages (phages), natural predators of bacteria, are becoming increasingly attractive
in medical and pharmaceutical applications. After their discovery almost a century ago, they …

The global rise of multi-drug resistant bacteria has resulted in the notion that an “antibiotic
apocalypse” is fast approaching. This has led to a number of well publicized calls for global …

Propelled by the overuse and inappropriate use of antibiotics, antimicrobial resistance is
now widespread in the environment, leaving us with limited drugs for treating a large …

Bacteriophages (phages) are viruses that infect bacterial hosts, and since their discovery
over a century ago they have been primarily exploited to control bacterial populations and to …

Phage therapy was implemented almost a century ago but was subsequently abandoned
when antibiotics emerged. However, the rapid emergence of drug-resistant, which has …

Background The therapeutic potential of bacteriophages has been debated since their first
isolation and characterisation in the early 20 th century. However, a lack of consistency in …

Antimicrobial resistance (AMR) in clinically priority pathogensis now a major threat to public
health worldwide. Phages are bacterial parasites that efficiently infect or kill specific strains …

Highlights•Understanding phage hijacking mechanism can facilitate the discovery of novel
antibacterials.•Phage genome-driven screening can reveal novel bacterial targets for small …

Phage therapy is the application of phages to bodies, substances, or environments to effect
the biocontrol of pathogenic or nuisance bacteria. To be effective, phages, minimally, must …

Bacterial infections have always been a threat to human health. The first available systemic
antibiotics, in early twentieth century, were initially seen as truly miraculous drugs, providing …