Osteosarcoma (OS) is the most common primary malignancy of bone and patients with
metastatic disease or recurrences continue to have very poor outcomes. Unfortunately, little …

Osteosarcoma is the most common primary bone cancer affecting children and adolescents
worldwide. Despite an incidence of three cases per million annually, it accounts for an …

Osteosarcoma (OS), the most common malignant tumor of bone, is presently treated with
multidrug neoadjuvant chemotherapy protocols, which allow to cure 60–65% of patients but …

In this review, recent advances in the clinical therapy of osteosarcoma, including results from
the European Osteosarcoma Intergroup trial demonstrating the efficacy of a short intensive …

An update on the conventional treatment of osteosarcoma, excluding secondary forms due
to malignancies by other diseases, as well as the parosteal-juxtacortical forms. The overall …

Osteosarcoma is the most frequent primary cancer of bone (incidence: 0.2–3/100 000/year).
The incidence is higher in adolescents (0.8–11/100 000/year at age 15–19), where it …

Osteozarcoma is the most common primary malignant tumour of bone, accounting for
approximately 35% of all primary sarcomas of bone. Its peak incidence is in the second …

Simple Summary Despite the adoption of aggressive, multimodal treatment schedules, the
cure rate of high-grade osteosarcoma (HGOS) has not significantly improved in the last 30 …

Background Osteosarcoma, a primary malignant bone tumor derived from mesenchymal
tissue, is the most common type of pleomorphic tumor that occurs in children and …

Osteosarcoma is the most common primary bone malignancy in adolescents. Its high
propensity to metastasize is the leading cause for treatment failure and poor prognosis …