Abstract The single-stranded oligonucleotide 5′-d (CCTCGCTCTC)(I) was reacted with the
antitumor trans platinum iminoderivative trans-[PtCl 2 {E-HN= C (OMe) Me} 2](trans-EE) and …

It has been shown recently that some analogues of clinically ineffective trans-
diamminedichloroplatinum (II)(transplatin) exhibit antitumor activity. This finding has inverted …

The reactions of the anticancer complex trans‐[PtCl2 {(E)‐HN C (OMe) Me} 2](trans‐EE)
with both single‐stranded and double‐stranded deoxyribonucleotides have been studied by …

Methionine ligand selectively promotes monofunctional adducts between trans - EE platinum
anticancer drug and guanine DNA base - Chemical Communications (RSC Publishing) …

Combined multidimensional nuclear magnetic resonance spectroscopy and electrospray
mass spectrometry was used to analyze the platinated DNA adduct of the phase II …

Increasing evidence indicates that sulfur-containing molecules can play important roles in
the activity of platinum anticancer drugs. Although nuclear DNA is retained to be the ultimate …

Recent findings that an analogue of clinically ineffective transplatin, trans-[PtCl2 (E-
iminoether) 2], exhibits antitumor activity has helped reevaluation of the empirical structure …

The DNA binding of the dinuclear platinum complex trans-[{Pt (NH3) 2Cl} 2μ-dpzm] 2+(di-
Pt), linked with the 4, 4′-dipyrazolylmethane (dpzm) linker, was examined by 1H and 195Pt …

In recent years, several exceptions to the rule that the presence of two good leaving groups
in cis positions of platinum complexes is a necessary condition for their antitumor activity …

The dinuclear platinum complexes [{trans-PtCl (NH3) 2} 2µ-{HNH2 (CH2) n NH2}](NO3) 2 [1,
1/t, t (n= 4, 6)] and [{cis-PtCl (NH3) 2} 2µ-{NH2 (CH2) n NH2}](NO3) 2 [1, 1/c, c (n= 4, 6)] …