Circular RNA circHERC4 as a novel oncogenic driver to promote tumor metastasis via the miR-556-5p/CTBP2/E-cadherin axis in colorectal cancer

J He, Z Chu, W Lai, Q Lan, Y Zeng, D Lu, S Jin… - Journal of hematology & …, 2021 - Springer
Background The main cause of death in colorectal cancer patients is metastasis.
Accumulating evidences suggest that circRNA plays pivotal roles in cancer initiation and …

circRAE1 promotes colorectal cancer cell migration and invasion by modulating miR-338-3p/TYRO3 axis

J Du, J Xu, J Chen, W Liu, P Wang, K Ye - Cancer cell international, 2020 - Springer
Background Growing evidence has revealed the involvement of circular RNAs (circRNAs) in
numerous carcinogenesis. However, the role of circRNAs in the cancer biology of colorectal …

CircRNA_0000392 promotes colorectal cancer progression through the miR-193a-5p/PIK3R3/AKT axis

H Xu, Y Liu, P Cheng, C Wang, Y Liu, W Zhou… - Journal of Experimental …, 2020 - Springer
Abstract Background Circular RNAs (circRNAs), important members of the noncoding RNA
family, have been recently revealed to play a role in the pathogenic progression of diseases …

CircPTK2 (hsa_circ_0005273) as a novel therapeutic target for metastatic colorectal cancer

H Yang, X Li, Q Meng, H Sun, S Wu, W Hu, G Liu, X Li… - Molecular cancer, 2020 - Springer
Background As a novel class of noncoding RNAs, circRNAs have been recently identified to
regulate tumorigenesis and aggressiveness. However, the function of circRNAs in colorectal …

CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA

B Yao, Q Zhang, Z Yang, F An, H Nie, H Wang, C Yang… - Molecular cancer, 2022 - Springer
Background Aberrant expression of circular RNAs (circRNAs) contributes to the initiation
and progression of human malignancies, but the underlying mechanisms remain largely …

CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer

T Jiang, H Wang, L Liu, H Song, Y Zhang, J Wang… - Molecular Cancer, 2021 - Springer
Background Accumulating studies have revealed that aberrant expression of circular RNAs
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …

RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer

XN Li, ZJ Wang, CX Ye, BC Zhao, ZL Li… - Journal of Experimental & …, 2018 - Springer
Abstract Background Circular RNA (circRNA) is a novel class of noncoding RNAs with
functions in various pathophysiological activities. However, the expression profiles and …

[HTML][HTML] RETRACTED ARTICLE: CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7

K Zeng, X Chen, MU Xu, X Liu, X Hu, T Xu… - Cell death & …, 2018 - ncbi.nlm.nih.gov
Mounting evidences indicate that circular RNAs (circRNAs) have a vital role in human
diseases, especially cancers. More recently, circHIPK3, a particularly abundant circRNA …

[HTML][HTML] CircRNA_0084927 promotes colorectal cancer progression by regulating miRNA-20b-3p/glutathione S-transferase mu 5 axis

F Liu, XL Xiao, YJ Liu, RH Xu, WJ Zhou… - World journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Colorectal cancer (CRC) is the third most common cancer and the second
most common cause of cancer-related death worldwide. The 5-year survival rate of patients …

Elevated levels of circRUNX1 in colorectal cancer promote cell growth and metastasis via miR-145-5p/IGF1 signalling

ZL Chen, XN Li, CX Ye, HY Chen… - OncoTargets and …, 2020 - Taylor & Francis
Background Emerging evidence suggests that circular RNAs (circRNAs) are vital regulators
in a range of cancers.“miRNA sponge” is the most reported role played by circRNAs in many …