[HTML][HTML] A general-purpose nanohybrid fabricated by polymeric Au (I)-peptide precursor to wake the function of peptide therapeutics
Peptide-derived nanocomposites have been exhibiting fascinating biological advantages,
including but not limited to excellent biocompatibility, biological degradation, high …
including but not limited to excellent biocompatibility, biological degradation, high …
A facile approach for synthesis and intracellular delivery of size tunable cationic peptide functionalized gold nanohybrids in cancer cells
Peptide-based drug delivery systems have become a mainstay in the contemporary
medicinal field, resulting in the design and development of better pharmaceutical …
medicinal field, resulting in the design and development of better pharmaceutical …
[HTML][HTML] Awakening p53 in vivo by D-peptides-functionalized ultra-small nanoparticles: Overcoming biological barriers to D-peptide drug delivery
Z Bian, J Yan, S Wang, Y Li, Y Guo, B Ma, H Guo… - Theranostics, 2018 - ncbi.nlm.nih.gov
Peptides are a rapidly growing class of therapeutics with many advantages over
conventional small molecule drugs. Dextrorotary (D)-peptides, with increased enzymatic …
conventional small molecule drugs. Dextrorotary (D)-peptides, with increased enzymatic …
N-Acetylation of Biodegradable Supramolecular Peptide Nanofilaments Selectively Enhances Their Proteolytic Stability for Targeted Delivery of Gold-Based …
Peptide materials are promising for various biomedical applications; however, a significant
concern is their lack of stability and rapid degradation in vivo due to non-specific proteolysis …
concern is their lack of stability and rapid degradation in vivo due to non-specific proteolysis …
Self‐assembly of therapeutic peptide into stimuli‐responsive clustered nanohybrids for cancer‐targeted therapy
Clinical translation of therapeutic peptides, particularly those targeting intracellular protein–
protein interactions (PPIs), has been hampered by their inefficacious cellular internalization …
protein interactions (PPIs), has been hampered by their inefficacious cellular internalization …
[HTML][HTML] A nano-predator of pathological MDMX construct by clearable supramolecular gold (I)-thiol-peptide complexes achieves safe and potent anti-tumor activity
S Yan, J Yan, D Liu, X Li, Q Kang, W You, J Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
As alternatives to small-molecular proteolysis-targeting chimeras (PROTAC), peptide-based
molecular glues (MG) are a broad range of dual-functional ligands that simultaneously bind …
molecular glues (MG) are a broad range of dual-functional ligands that simultaneously bind …
Reconfigurable peptide nanotherapeutics at tumor microenvironmental pH
ZY Qiao, WJ Zhao, YJ Gao, Y Cong… - … applied materials & …, 2017 - ACS Publications
Peptide nanomaterials have recently attracted considerable interest in the biomedical field.
However, their poor bioavailability and less powerful therapeutic efficacy hamper their …
However, their poor bioavailability and less powerful therapeutic efficacy hamper their …
Cell penetrating peptide (CPP) gold (iii)–complex–bioconjugates: from chemical design to interaction with cancer cells for nanomedicine applications
C Arib, A Griveau, J Eyer, J Spadavecchia - Nanoscale Advances, 2022 - pubs.rsc.org
This study promotes an innovative synthesis of a nanotheragnostic scaffold capable of
targeting and destroying pancreatic cancer cells (PDAC) using the Biotinylated NFL-TBS. 40 …
targeting and destroying pancreatic cancer cells (PDAC) using the Biotinylated NFL-TBS. 40 …
Multi-domain short peptide molecules for in situ synthesis and biofunctionalization of gold nanoparticles for integrin-targeted cell uptake
We describe design and synthesis model of multidomain (modular) peptides (MDPs), which
direct a reaction cascade coupling the synthesis and surface functionalization of gold …
direct a reaction cascade coupling the synthesis and surface functionalization of gold …
Shuttling gold nanoparticles into tumoral cells with an amphipathic proline‐rich peptide
S Pujals, NG Bastús, E Pereiro… - …, 2009 - Wiley Online Library
Golden bullets: The amphipathic proline‐rich cell‐penetrating peptide sweet arrow peptide
(SAP) is able to transport 12 nm gold nanoparticles efficiently into HeLa cells, as observed …
(SAP) is able to transport 12 nm gold nanoparticles efficiently into HeLa cells, as observed …