Periodontal acidification contributes to tooth pain hypersensitivity during orthodontic tooth movement
A Osada, S Hitomi, A Nakajima, Y Hayashi… - Neuroscience …, 2022 - Elsevier
Tooth movements associated with orthodontic treatment often cause tooth pain. However,
the detailed mechanism remains unclear. Here, we examined the involvement of periodontal …
the detailed mechanism remains unclear. Here, we examined the involvement of periodontal …
The role of acid-sensing ion channel 3 in the modulation of tooth mechanical hyperalgesia induced by orthodontic tooth movement
H Yang, D Shan, Y Jin, H Liang, L Liu, Y Guan, C Chen… - Neuroscience, 2020 - Elsevier
This study aimed to explore the role of acid-sensing ion channel 3 (ASIC3) in the modulation
of tooth mechanical hyperalgesia induced by orthodontic tooth movement. In male Sprague …
of tooth mechanical hyperalgesia induced by orthodontic tooth movement. In male Sprague …
The role of periodontal ASIC3 in orofacial pain induced by experimental tooth movement in rats
M Gao, H Long, W Ma, L Liao, X Yang… - European journal of …, 2016 - academic.oup.com
Objectives: This study aimed to clarify the roles of Acid-sensing ion channel 3 (ASIC3) in
orofacial pain following experimental tooth movement. Materials and methods: Sixty male …
orofacial pain following experimental tooth movement. Materials and methods: Sixty male …
Retrograde nerve growth factor signaling modulates tooth mechanical hyperalgesia induced by orthodontic tooth movement via acid-sensing ion channel 3
Orthodontic tooth movement elicits alveolar bone remodeling and orofacial pain that is
manifested by tooth mechanical hyperalgesia. Nerve growth factor (NGF) is upregulated in …
manifested by tooth mechanical hyperalgesia. Nerve growth factor (NGF) is upregulated in …
Orthodontic force facilitates cortical responses to periodontal stimulation
E Horinuki, M Shinoda, N Shimizu… - Journal of Dental …, 2015 - journals.sagepub.com
Somatosensory information derived from the periodontal ligaments plays a critical role in
identifying the strength and direction of occlusal force. The orthodontic force needed to move …
identifying the strength and direction of occlusal force. The orthodontic force needed to move …
Neural mechanisms of nociception during orthodontic treatment
M Kobayashi, E Horinuki - Journal of Oral Science, 2017 - jstage.jst.go.jp
Orthodontic tooth movement is accompanied by inflammatory responses in the periodontal
ligament. Chemical mediators such as interleukin-1β have key roles in nociception around …
ligament. Chemical mediators such as interleukin-1β have key roles in nociception around …
Orthodontic tooth movement-activated sensory neurons contribute to enhancing osteoclast activity and tooth movement through sympathetic nervous signalling
H Kondo, M Kondo, K Hayashi… - European Journal of …, 2022 - academic.oup.com
Objectives Orthodontic tooth movement (OTM) increases sympathetic and sensory
neurological markers in periodontal tissue. However, the relationship between the …
neurological markers in periodontal tissue. However, the relationship between the …
Role of TRPV 1 and ASIC 3 channels in experimental occlusal interference‐induced hyperalgesia in rat masseter muscle
XX Xu, Y Cao, TT Ding, KY Fu, Y Li… - European Journal of …, 2016 - Wiley Online Library
Background Masticatory muscle pain may occur following immediate occlusal alteration by
dental treatment. The underlying mechanisms are poorly understood. Transient receptor …
dental treatment. The underlying mechanisms are poorly understood. Transient receptor …
Orthodontic treatment-induced temporal alteration of jaw-opening reflex excitability
A Sasaki, N Hasegawa, K Adachi… - Journal of …, 2017 - journals.physiology.org
The impairment of orofacial motor function during orthodontic treatment needs to be
addressed, because most orthodontic patients experience pain and motor excitability would …
addressed, because most orthodontic patients experience pain and motor excitability would …
Different Therapeutic Effects of CO2 and Diode Laser Irradiation on Tooth Movement-Related Pain
T Tsuchiya, N Hasegawa, M Yugawa, A Sasaki… - Frontiers in …, 2020 - frontiersin.org
Although orthodontic treatment is common, orthodontic force often induced pain. Low-level
laser therapy (LLLT) has been investigated to improve therapeutic comfort. In dentistry, LLLT …
laser therapy (LLLT) has been investigated to improve therapeutic comfort. In dentistry, LLLT …