Objectives: To evaluate the correlation between pain and tissue reactions during induced
tooth movement (ITM). Materials and Methods: Forty-two male Wistar rats (Rattus …

Various stimuli induce pain when applied to the surface of exposed dentin. However, the
mechanisms underlying dentinal pain remain unclear. We investigated intercellular signal …

Background: During orthodontic tooth movement, the early response of periodontal tissues
to mechanical stress involves an acute inflammatory response, with a sequence …

Background The pain caused by orthodontic treatment has been considered as tough
problems in orthodontic practice. Danggui-shaoyao-san (DSS) is a traditional Chinese …

Due, in part, to the unique structure of the tooth, dental pain is initiated via distinct
mechanisms. Here we review recent advances in our understanding of inflammatory tooth …

Objectives The early phase of orthodontic tooth movement involves acute inflammatory
response that may induce bone resorption. The aim of this study was to localize and quantify …

Temporomandibular joint (TMJ) disorder caused by occlusal trauma is one of the most
controversial topics in dentistry. Experimental traumatic occlusion (ETO) induced by metal …

Nociception by orthodontic tooth movement stimulate Trigeminal nerve free endings in
periodontal ligament (PDL), and neuropeptides such as substance P and CGRP are …

Mechanical force is not the only means to cause tooth movement, but just one kind of stimuli
for it. Biological stimuli, with potential of accelerating alveolar bone remodeling, other than …

Purpose The aim of this prospective study was to evaluate the relationship between pain
intensity and concentrations of salivary pain and stress biomarkers during orthodontic tooth …