Several pathologies such as neurodegeneration and cancer are associated with aging,
which is affected by many genetic and environmental factors. Healthy aging conceives …

Aging constitutes the key risk factor for age‐related diseases such as cancer and
cardiovascular and neurodegenerative disorders. Human longevity and healthy aging are …

The FoxO family of Forkhead transcription factors functions at the interface of tumor
suppression, energy metabolism, and organismal longevity. FoxO factors are key …

Background: The gene FOXO3, encoding the transcription factor forkhead box O-3 (FoxO3),
is one of only two for which genetic polymorphisms have exhibited consistent associations …

FOXO (Forkhead box O) transcription factors constitute an evolutionally conserved subgroup
within the large Forkhead family of transcription regulators. FOXO factors are important …

Fork head box O (FOXO) transcription factor is a key player in an evolutionarily conserved
pathway. The mammalian FOXO family consists of FOXO1, 3, 4 and 6, are highly similar in …

FOXO family of proteins are transcription factors involved in many physiological and
pathological processes including cellular homeostasis, stem cell maintenance, cancer …

Aging happens to all of us as we live. Thanks to the improved living standard and discovery
of life-saving medicines, our life expectancy has increased substantially across the world in …

Abstract The FoxO family of Forkhead transcription factors plays an important role in
longevity and tumor suppression by upregulating target genes involved in stress resistance …

FOXO transcription factors (FOXO s) are central regulators of lifespan across species, yet
they also have cell‐specific functions, including adult stem cell homeostasis and immune …