Recurrent genetic abnormalities are important prognostic markers in acute myeloid
leukemias (AML). The World Health Organization classification recognizes 7 categories of …

In this paper, we report on a 9-year-old girl with acute nonlymphocytic leukemia (FAB-M5)
with a rare chromosome abnormality, t (11; 23)(q21; p11). Peripheral blood showed Hb 7.5 …

The 8p11 myeloproliferative syndrome (EMS) is a rare yet aggressive disorder molecularly
characterized by disruption of the fibroblast growth factor receptor (FGFR1) gene [1] …

Objective To investigate the clinical and laboratory characteristics of acute myeloid leukemia
(AML) with t (16; 21)(p11; q22) translocation. Methods Two patients diagnosed by …

We present a 6-year-old girl with acute myeloid leukemia (AML)-M5, normal karyotype at the
time of diagnosis, and t (1; 3)(p36; q21) at relapse. The t (1; 3)(p36; q21) is a rare but …

Chromosomal rearrangements involving the MLL gene (approved symbol: KMT2A) at 11q23
are associated with different types of hematological malignancies, with more than 70 fusion …

Discussion Translocation (16; 21)(p11; q22) is a uncommon but recurrent cytogenetic
abnormality described in acute myeloid leukaemia (AML) and one case of chronic myeloid …

The reciprocal translocation between chromosomes 8 and 21 with breakpoints in 8q22 and
21q22 was first reported by Rowley, in 1973, 1 in a subgroup of patients with acute myeloid …

Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow. It is the most
common type of acute leukemia in adults. This type of cancer usually gets worse quickly if it …

Acute myeloid leukaemia (AML) with t (8; 21) is a common AML subtype and it is associated
with a favourable prognosis. Variants of this translocation, involving other chromosomes in …