Although the translocation (8; 21) is the single most common structural rearrangement
reported in acute myeloblastic leukemia (AML), it is rarely seen in AML FAB type M5. We …

The t (7; 11)(p15; p15) translocation is a recurrent genetic abnormality associated with acute
myelogenous leukemia (AML). The translocation results in a fusion between the nucleoporin …

Cytogenetic abnormalities play an important role in diagnosis, classification and prognosis
in acute myeloid leukemia (AML). Nevertheless, several chromosome abnormalities have …

The complex variants of t (8; 21) involving chromosomes 8 and 21 as well as a variable
chromosome account for 1.1∼ 5% of acute myeloid leukemia (AML) patients. This paper …

Dear Editor, AML is a group of heterogeneous diseases derived from various cytogenetic
and molecular abnormalities that are significant for diagnosis, treatment, and prognosis in …

Acute myeloid leukemia (AML) with t (8; 21)(q22; q22) generating the AML1/ETO fusion
gene on 8q22 is a distinct type of AML t (8; 21) category (WHO)/AML-M2 (FAB), generally …

Acute Myeloid Leukemia with Minimal Differentiation with translocation t(16;21)(p11;q22):
Case report and review of the literatu Page 1 The t(16;21)(p11;q22) carry the FUS-ERG fusion …

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML)
characterised by the proliferation of malignant promyelocytes with mature myeloid …

Abstract The t (8; 21)(q22; q22) is the most common translocation in acute myeloid leukemia
(AML). We describe the clinicopathologic and cytogenetic profile of 117 patients with t (8; 21) …

We describe the cytogenetic abnormality of t (15; 17)(q22; q21) in a case of acute myeloid
leukemia without evidence of PML/RARα rearrangement on molecular analysis. Due to its …