Structural abnormalities in the long arm of chromosome 3 have been detected in 7–10% of
patients with acute myelogenous leukemia (AML) or myelodysplastic syndromes. Patients …

Since its first description by Hillestad in 1957, acute promyelocytic leukemia (APML) has
been recognized as a distinct subtype of acute myeloid leukemia (AML) because of its …

Twenty-three patients with de novo acute myeloid leukemia (AML) and t (8; 21)(q22; q22),
including 2 children aged 7 and 14 and 21 adults aged 16 to 68 (median 29), were treated …

We read with interest a recent paper by Estalilla et al.[1] who reported 10 in four patients with
acute leukemia. However, with the possible exception of case 1, where the concurrent loss …

AML with translocation t (3; 5) belongs to the “AML with myelodysplasia-related changes”
defined in the 2008 WHO classification. 1 The incidence of this balanced abnormality is less …

Abstract Acute Myelogeneous Leukemia (AML) is a heterogeneous disease with respect to
morphology, immunophenotype, and genetic rearrangements. Multiple recurrent …

The boy, was detected with acute promyelocytic leukaemia (APL) and studies revealed PML-
retinoic acid receptor-α (RARA) rearrangement in 70% of 200 interphase nuclei, post initial …

We describe a patient with acute promyelocytic leukemia (APL) who was successfully
induced into remission with all-trans reti-noic acid (ATRA) and idarubicin, but developed …

We present a novel, rare but recurrent variant three way translocation of t (8; 21), t (8; 16;
21)(q22; q24; q22), as a primary cytogenetic abnormality, resulting in AML1/ETO fusion …

ABSTRACT The t (2; 19) translocation is rare in acute myeloid leukemia (AML). We report a
case of a 30-year-old male with acute monocytic leukemia (AML-M5) with t (2; 19) …