Superoxide dismutases and their impact upon human health
F Johnson, C Giulivi - Molecular aspects of medicine, 2005 - Elsevier
Superoxide dismutases (SOD), a group of metal-containing enzymes, have a vital anti-
oxidant role in human health, conferred by their scavenging of one of the reactive oxygen …
oxidant role in human health, conferred by their scavenging of one of the reactive oxygen …
Superoxide dismutases (SODs) and SOD mimetics
GEO Borgstahl, RE Oberley-Deegan - Antioxidants, 2018 - mdpi.com
Superoxide dismutase (SOD) is the only known enzyme to directly scavenge a free radical.
Specifically, SOD dismutes superoxide to oxygen and hydrogen peroxide with high …
Specifically, SOD dismutes superoxide to oxygen and hydrogen peroxide with high …
Superoxide dismutases: role in redox signaling, vascular function, and diseases
T Fukai, M Ushio-Fukai - Antioxidants & redox signaling, 2011 - liebertpub.com
Excessive reactive oxygen species Revised abstract, especially superoxide anion (O2•−),
play important roles in the pathogenesis of many cardiovascular diseases, including …
play important roles in the pathogenesis of many cardiovascular diseases, including …
SOD, oxidative stress and human pathologies: a brief history and a future vision
JM McCord, MA Edeas - Biomedicine & Pharmacotherapy, 2005 - Elsevier
Superoxide dismutase (SOD) has now been known for 35 years. While the superoxide
radical and SOD have been implicated in many disease states including inflammatory …
radical and SOD have been implicated in many disease states including inflammatory …
A review of the catalytic mechanism of human manganese superoxide dismutase
J Azadmanesh, GEO Borgstahl - Antioxidants, 2018 - mdpi.com
Superoxide dismutases (SODs) are necessary antioxidant enzymes that protect cells from
reactive oxygen species (ROS). Decreased levels of SODs or mutations that affect their …
reactive oxygen species (ROS). Decreased levels of SODs or mutations that affect their …
Superoxide dismutase--applications and relevance to human diseases.
R Noor, S Mittal, J Iqbal - Medical science monitor: international …, 2002 - europepmc.org
Reactive oxygen species, such as superoxide radicals, are thought to underlie the
pathogenesis of various diseases. Almost 3 to 10% of the oxygen utilized by tissues is …
pathogenesis of various diseases. Almost 3 to 10% of the oxygen utilized by tissues is …
Expanding roles of superoxide dismutases in cell regulation and cancer
Highlights•Superoxide dismutases (SODs) have important regulatory functions in
metabolism, signalling and transcription.•SODs are crucial for cancer cell growth …
metabolism, signalling and transcription.•SODs are crucial for cancer cell growth …
Regulation of superoxide dismutase genes: implications in disease
L Miao, DKS Clair - Free Radical Biology and Medicine, 2009 - Elsevier
Numerous short-lived and highly reactive oxygen species (ROS) such as superoxide (O2−),
hydroxyl radical, and hydrogen peroxide are continuously generated in vivo. Depending …
hydroxyl radical, and hydrogen peroxide are continuously generated in vivo. Depending …
Superoxide dismutase 1 in health and disease: how a frontline antioxidant becomes neurotoxic
Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing superoxide
breakdown and is important for most forms of eukaryotic life. The evolution of aerobic …
breakdown and is important for most forms of eukaryotic life. The evolution of aerobic …
The basic and applied aspects of superoxide dismutase
Superoxide dismutase (SOD) is among the most potent antioxidants known in nature and is
an important constituent of cellular defence against oxidative stress. The enzyme shows …
an important constituent of cellular defence against oxidative stress. The enzyme shows …
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