The renin‐angiotensin system (RAS) is a critical regulator of hypertension, primarily through
the actions of the vasoactive peptide Ang II, which is generated by the action of angiotensin …

Angiotensin‐converting enzyme 2 (ACE2) shares some homology with angiotensin‐
converting enzyme (ACE) but is not inhibited by ACE inhibitors. The main role of ACE2 is the …

Repletion of ACE2's activities offers a new strategy to complement current clinical
interventions in treating hypertension, renal and cardiovascular disease. In particular …

Angiotensin-converting enzyme 2: implications for blood pres... : Current Opinion in Nephrology
and Hypertension Angiotensin-converting enzyme 2: implications for blood pressure and kidney …

Angiotensin-converting enzyme 2 (ACE2) is the first human homologue of ACE to be
described. ACE2 is a type I integral membrane protein that functions as a carboxypeptidase …

Angiotensin-converting enzyme (ACE) is a zinc metalloproteinase and a key regulator of the
renin–angiotensin system (RAS). ACE2 is a newly described enzyme identified in rodents …

The renin-angiotensin system (RAS) plays a major role in the pathophysiology of
cardiovascular disorders. Angiotensin II (Ang-II), the final product of this pathway, is known …

The renin-angiotensin system (RAS) is currently considered a central regulator of blood
pressure in the mammalian organism. Even though renin was first described in 1898, it was …

Abstract Angiotensin-converting enzyme 2 (ACE2), discovered as a homologue of ACE, acts
as its physiological counterbalance providing homeostatic regulation of circulating …

The renin–angiotensin system (RAS) is critically involved in cardiovascular and renal
function and in disease conditions, and has been shown to be a far more complex system …