Previous studies have identified some key amino acid residues in scorpion toxins blocking
potassium channels. In particular, the most numerous toxins belonging to the α-KTx family …

Potassium channels play a key role in regulating many physiological processes, thus,
alterations in their proper functioning can lead to the development of several diseases …

Scorpion toxins are invaluable pharmacological tools for studying ion channels and
potential drugs for channelopathies. The long-chain toxins from scorpion venom with four …

Maurotoxin (MTX) is a 34‐residue toxin that has been isolated from the venom of the
chactidae scorpion Scorpio maurus palmatus, and characterized. Together with Pi1 and …

Three 35-amino acid peptide K channel toxins (pandinotoxins) were purified from the venom
of the scorpion Pandinus imperaton the toxins are designated pandinotoxin(PiTX)-Ka, PiTX …

An important and exciting challenge in the postgenomic era is to understand the functions of
newly discovered proteins based on their structures. The main thrust is to find the common …

We have purified and characterized two peptides, named KAaH1 and KAaH2 (AaH
polypeptides 1 and 2 active on K+ channels, where AaH stands for Androctonus australis …

Hemitoxin (HTX) is a new K+ channel blocker isolated from the venom of the Iranian
scorpion Hemiscorpius lepturus. It represents only 0.1% of the venom proteins, and …

Opisthacanthus cayaporum belongs to the Liochelidae family, and the scorpions from this
genus occur in southern Africa, Central America and South America and, therefore, can be …

Abstract Agitoxin 2 (AgTx2) is a 38‐residue scorpion toxin, cross‐linked by three disulfide
bridges, which acts on voltage‐gated K+ (Kv) channels. Maurotoxin (MTX) is a 34‐residue …