[PDF][PDF] Effect of Maternal DEHP Exposure on Lipid Metabolism in Adult Male Rats and the Antagonistic Effect of Genistein

ZY Bo, LIJ Li, T Jie, NAX Lin - Biomedical and Environmental …, 2024 - besjournal.com
Lipid metabolism refers to the biochemical processes involved in synthesising, storing,
utilising, and breaking down lipids in living organisms. Lipids are essential for various …

Perinatal DEHP exposure modulates pituitary estrogen receptor α and β expression altering lactotroph and somatotroph cell growth in prepuberal and adult male rats

PA Pérez, J Toledo, F Picech, JP Petiti… - Food and Chemical …, 2021 - Elsevier
Phthalates are synthetic chemicals widely used to make polyvinylchloride (PVC) soft and
flexible. Of these, Di-(2-ethylhexyl) phthalate (DEHP) is the most commonly used, with high …

Transcriptomics and metabonomics analyses of maternal DEHP exposure on male offspring

Y Zhang, W Zhang, X Fu, F Zhou, H Yu, X Na - Environmental Science and …, 2018 - Springer
The objectives of this study were to evaluate the effect of maternal Di-2-ethylhexyl phthalate
(DEHP) exposure on male offspring and to explore the mechanism of changes with the …

Effects of endocrine disruptors on the expression of estrogen receptors in ovary and uterus from immature rats

KY Lee, SH Lee - Development and Reproduction, 2006 - koreascience.kr
Although some phytoes rogens might have beneficiary rather than adverse effects, most
endocrine disrupting compounds (EDCs) are considered to be harmful to human and wildlife …

[PDF][PDF] The development of metabolic derangement in male offspring after perinatal exposure to di-(2-ethylhexyl) phthalate

Y Yang, M Park, EJ Lee, Y Hong - Biomed Environ Sci, 2018 - academia.edu
The prevalence of obesity and type 2 diabetes mellitus (T2DM) has been increasing
throughout the world over the past 20 years. Environmental chemicals known to regulate the …

DEHP and DINP induce tissue-and gender-specific disturbances in fatty acid and lipidomic profiles in neonatal mice: a comparative study

Y Huang, F Sun, H Tan, Y Deng, Z Sun… - … science & technology, 2019 - ACS Publications
Di-isononyl phthalate (DINP) is considered one of the main industrial alternatives to di (2-
ethylhexyl) phthalate (DEHP), a well-known chemical with various toxic effects including the …

Exposure to di-(2-ethylhexyl) phthalate reduces secretion of GDNF via interfering with estrogen pathway and downregulating ERK/c-fos signaling pathway in …

J Wang, X Li, C Wang, Y Li, J Wang, R Fang… - Food and Chemical …, 2021 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is a typical endocrine-disrupting chemical
(EDC) that can increase the risk of central nervous system disease. This study aimed to …

Maternal exposure to di-(2-ethylhexyl) phthalate exposure deregulates blood pressure, adiposity, cholesterol metabolism and social interaction in mouse offspring

KI Lee, CW Chiang, HC Lin, JF Zhao, CT Li… - Archives of …, 2016 - Springer
Long-term exposure to di-(2-ethylhexyl) phthalate (DEHP) is highly associated with
carcinogenicity, fetotoxicity, psychological disorders and metabolic diseases, but the …

Prenatal Exposure to the Endocrine Disrupting Chemical DEHP Impacts Reproduction-Related Gene Expression in the Pituitary

X Ge, K Weis, L Raetzman - Journal of the Endocrine Society, 2021 - academic.oup.com
Phthalates are chemicals used in various common products including plastics and medical
devices, leading to widespread contact. Phthalate exposure during embryonic development …

Lack of adverse effects in the F1 offspring maternally exposed to genistein at human intake dose level

KS Kang, JH Che, YS Lee - Food and chemical toxicology, 2002 - Elsevier
Recently there has been growing concern about endocrine disrupters (ED) derived from
synthetic and natural chemicals. It has been argued that ED might cause developmental …