Multi-omics approach reveals influenza-A virus target genes associated genomic, clinical and immunological characteristics in cancers

J Wang, Y Liao, P Yang, W Ye, Y Liu, C Xiao, W Liao… - 2023 - researchsquare.com
Influenza A virus has been shown to be closely linked to diverse malignancies and may
work as an oncovirus. However, the specific role of influenza A virus as well as its target …

Comprehensive Transcriptomic Analysis Identifies Cellular Immune Response Against Influenza A Virus Infection

A Zhou, X Dong, M Liu, B Tang - Available at SSRN 3736007 - papers.ssrn.com
Influenza A virus (IAV) has the higher genetic variation and reassortment, the traditional
vaccine and virus-directed antiviral strategies have hardly shown successful efficacy and …

Comprehensive transcriptomic analysis identifies novel antiviral factors against influenza A virus infection

A Zhou, X Dong, M Liu, B Tang - Frontiers in immunology, 2021 - frontiersin.org
Influenza A virus (IAV) has a higher genetic variation, leading to the poor efficiency of
traditional vaccine and antiviral strategies targeting viral proteins. Therefore, developing …

Identification of critical genes and pathways for influenza A virus infections via bioinformatics analysis

G Chen, H Li, M Hao, X Li, Y Dong, Y Zhang, X Liu… - Viruses, 2022 - mdpi.com
Influenza A virus (IAV) requires the host cellular machinery for many aspects of its life cycle.
Knowledge of these host cell requirements not only reveals molecular pathways exploited …

Global transcriptome analysis of H5N1 influenza virus-infected human cells

Y Cao, K Zhang, L Liu, W Li, B Zhu, S Zhang, P Xu… - Hereditas, 2019 - Springer
Abstract Background Influenza A virus (IAV) belongs to the Orthomyxoviridae family. IAV
causes a highly contagious respiratory disease in humans that exacts severe economic …

Proteomic analysis at the subcellular level for host targets against influenza A virus (H1N1)

H Zhao, J Yang, K Li, X Ding, R Lin, Y Ma, J Liu… - Antiviral research, 2013 - Elsevier
Influenza viruses (IVs) trigger a series of intracellular signaling events and induce complex
cellular responses from the infected host cell. Accumulating evidence suggests that host cell …

Bioinformatics analysis in identifying significantly expressed immune related genes in influenza A virus infection

A Olaniyi, A Oluwabunmi, O Oluwatobi - bioRxiv, 2022 - biorxiv.org
This study is done to identify significantly expressed genes of influenza A virus infection in
human, facilitated by the idea of checking for the presence of immune related genes in these …

Acute influenza infection promotes lung tumor growth by reprogramming the tumor microenvironment

I Garmendia, A Varthaman, S Marmier, M Angrini… - Cancer Immunology …, 2023 - AACR
One billion people worldwide get flu every year, including patients with non–small cell lung
cancer (NSCLC). However, the impact of acute influenza A virus (IAV) infection on the …

Identification of potential host proteins for influenza A virus based on topological and biological characteristics by proteome-wide network approach

YH Lai, ZC Li, LL Chen, Z Dai, XY Zou - Journal of proteomics, 2012 - Elsevier
A proteome-wide network approach was performed to characterize significant patterns of
influenza A virus (IAV)–human interactions, and to further identify potentially valuable targets …

Multi-omics analysis of N6-methyladenosine reader IGF2BP3 as a promising biomarker in pan-cancer

P Chen, J Xu, Z Cui, S Wu, T Xie, X Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Background Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) has been
reported to exhibit an oncogenic effect as an RNA-binding protein (RBP) by promoting tumor …