Cytokine and adhesion molecule expression in primary human endothelial cells stimulated with fever-range hyperthermia

A Shah, E Unger, MD Bain, R Bruce… - International Journal …, 2002 - Taylor & Francis
Migration of blood-borne lymphocytes into lymphoid tissues and sites of inflammation is
initiated by vascular adhesion molecules and proinflammatory cytokines. Previous in vivo …

Fever-range hyperthermia dynamically regulates lymphocyte delivery to high endothelial venules

SS Evans, WC Wang, MD Bain, R Burd… - Blood, The Journal …, 2001 - ashpublications.org
Fever is associated with increased survival during acute infection, although its mechanism of
action is largely unknown. This study found evidence of an unexpectedly integrated …

Fever-range hyperthermia enhances L-selectin-dependent adhesion of lymphocytes to vascular endothelium

WC Wang, LM Goldman, DM Schleider… - The Journal of …, 1998 - journals.aai.org
The L-selectin leukocyte adhesion molecule plays an important role in controlling leukocyte
extravasation in peripheral lymph nodes and at sites of tissue injury or infection. Although …

Fever-range hyperthermia stimulates alpha4beta7 integrin-dependent lymphocyte-endothelial adhesion

SS Evans, MD Bain, WC Wang - International journal of …, 2000 - Taylor & Francis
Migration of blood-borne lymphocytes into lymphoid tissues is initiated by the Lselectin and
alpha4beta7 integrin adhesion molecules. Previous studies have shown that L-selectin …

Impact of fever-range thermal stress on lymphocyte-endothelial adhesion and lymphocyte trafficking

MM Appenheimer, Q Chen, RA Girard… - Immunological …, 2005 - Taylor & Francis
The evolutionarily conserved febrile response has been associated with improved survival
during infection in endothermic and ectothermic species although its protective mechanism …

Dynamic control of lymphocyte trafficking by fever-range thermal stress

Q Chen, DT Fisher, SA Kucinska, WC Wang… - Cancer Immunology …, 2006 - Springer
Migration of blood-borne lymphocytes into tissues involves a tightly orchestrated sequence
of adhesion events. Adhesion molecules and chemokine receptors on the surface of …

Hyperthermia attenuates TNF-alpha-induced up regulation of endothelial cell adhesion molecules in human arterial endothelial cells

N Nakabe, S Kokura, M Shimozawa… - International journal …, 2007 - Taylor & Francis
Background and aim: The activation of NF-κB induces production of inflammatory cytokines
and up regulation of endothelial cell adhesion molecules (ECAM). ECAM (eg, E-selectin …

Targeted regulation of a lymphocyte-endothelial-interleukin-6 axis by thermal stress

SS Evans, DT Fisher, JJ Skitzki… - International journal of …, 2008 - Taylor & Francis
Immune protection from microbial invaders or malignant progression is dependent on the
ability of lymphocytes to efficiently traffic across morphologically and biochemically distinct …

Suppressive effects of anti-inflammatory agents on human endothelial cell activation and induction of heat shock proteins

A Amberger, M Hala, M Saurwein-Teissl, B Metzler… - Molecular …, 1999 - Springer
Background Studies from our laboratory have shown that the earliest stages of
atherosclerosis may be mediated by an autoimmune reaction against heat shock protein 60 …

Thermal facilitation of lymphocyte trafficking involves temporal induction of intravascular ICAM-1

Q Chen, Q Chen, MM Appenheimer, JB Muhitch… - …, 2009 - Taylor & Francis
Objective: Fever is associated with improved survival, although its beneficial mechanisms
are poorly understood. Previous studies indicate that the thermal element of fever augments …