HDL and ApoA-I inhibit antigen presentation-mediated T cell activation by disrupting lipid rafts in antigen presenting cells

S Wang, S Yuan, D Peng, S Zhao - Atherosclerosis, 2012 - Elsevier
OBJECTIVE: Depletion of cholesterol by methyl-β-cyclodextrin (MCD) on peptide-loaded
antigen presenting cells (APCs) inhibits antigen presentation and T cell activation. However …

HDL and adaptive immunity: a tale of lipid rafts

GD Norata, AL Catapano - Atherosclerosis, 2012 - air.unimi.it
HDL and adaptive immunity : a tale of lipid rafts IRIS SUrplus Home Sfoglia Macrotipologie &
tipologie Autore Titolo Riviste Serie Settore Scientifico Disciplinare Tipologia IT Italiano Italiano …

High-density lipoprotein affects antigen presentation by interfering with lipid raft: a promising anti-atherogenic strategy

SH Wang, SG Yuan, DQ Peng… - Clinical & Experimental …, 2010 - academic.oup.com
Atherosclerosis is a chronic inflammatory disease. Immunomodulation of atherosclerosis
emerges as a promising approach to prevention and treatment of this widely prevalent …

High density lipoprotein biogenesis, cholesterol efflux, and immune cell function

MG Sorci-Thomas, MJ Thomas - Arteriosclerosis, thrombosis, and …, 2012 - Am Heart Assoc
This review provides a summary of recent research on the role of high-density lipoprotein
(HDL)/apolipoprotein AI cholesterol efflux and immune cell function. Plasma concentrations …

HDL and immunomodulation: an emerging role of HDL against atherosclerosis

B Yu, S Wang, D Peng, S Zhao - Immunology and cell biology, 2010 - Wiley Online Library
Changes in plasma lipoprotein profiles, particularly low levels of high‐density lipoprotein
(HDL) cholesterol, are associated with several inflammatory and immune diseases …

[HTML][HTML] Apolipoprotein E-containing HDL decreases caspase-dependent apoptosis of memory regulatory T lymphocytes

L Atehortua, J Morris, SE Street, N Bedel… - Journal of Lipid …, 2023 - ASBMB
Plasma levels of HDL cholesterol are inversely associated with CVD progression. It is
becoming increasingly clear that HDL plays important roles in immunity that go beyond its …

[HTML][HTML] Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL [S]

H Tavori, YR Su, PG Yancey, I Giunzioni… - Journal of lipid …, 2015 - ASBMB
Tissue cholesterol accumulation, macrophage infiltration, and inflammation are features of
atherosclerosis and some forms of dermatitis. HDL and its main protein, apoAI, are …

Apolipoprotein AI inhibits chemotaxis, adhesion, activation of THP-1 cells and improves the plasma HDL inflammatory index

L Wang, WZ Chen, MP Wu - Cytokine, 2010 - Elsevier
The anti-inflammatory effects of high density lipoprotein (HDL) are well described, however,
such effects of Apolipoprotein AI (ApoA-I) are less studied. Building on our previous study …

Cholesterol-independent suppression of lymphocyte activation, autoimmunity, and glomerulonephritis by apolipoprotein AI in normocholesterolemic lupus-prone mice

LL Black, R Srivastava, TR Schoeb… - The Journal of …, 2015 - journals.aai.org
Apolipoprotein (Apo) AI, the major lipid-binding protein of high-density lipoprotein, can
prevent autoimmunity and suppress inflammation in hypercholesterolemic mice by …

[HTML][HTML] Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity [S]

T Vaisar, C Tang, I Babenko, P Hutchins… - Journal of lipid …, 2015 - ASBMB
Recent studies demonstrate that HDL's ability to promote cholesterol efflux from
macrophages associates strongly with cardioprotection in humans independently of HDL …