[HTML][HTML] p38 MAPK and PI3K/AKT signalling cascades inParkinson's disease
SK Jha, NK Jha, R Kar, RK Ambasta… - International journal of …, 2015 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a chronic neurodegenerative condition which has the second
largest incidence rate among all other neurodegenerative disorders barring Alzheimer's …
largest incidence rate among all other neurodegenerative disorders barring Alzheimer's …
[HTML][HTML] Role of mitogen activated protein kinase signaling in Parkinson's disease
Parkinson's disease (PD) is a neurodegenerative disorder caused by insufficient dopamine
production due to the loss of 50% to 70% of dopaminergic neurons. A shortage of dopamine …
production due to the loss of 50% to 70% of dopaminergic neurons. A shortage of dopamine …
[HTML][HTML] The PI3K-AKT pathway: A plausible therapeutic target in Parkinson's disease
Parkinson's disease is a common progressive and multifactorial neurodegenerative disease,
characterized by the loss of midbrain dopaminergic neurons. Numerous pathological …
characterized by the loss of midbrain dopaminergic neurons. Numerous pathological …
[HTML][HTML] P38 mitogen-activated protein kinase and Parkinson's disease
J He, W Zhong, M Zhang, R Zhang… - Translational …, 2018 - degruyter.com
Parkinson's disease, the second major neurodegenerative disease, has created a great
impact on the elder people. Although the mechanisms underlying Parkinson's disease are …
impact on the elder people. Although the mechanisms underlying Parkinson's disease are …
[HTML][HTML] PI3K/AKT signaling mediated by G protein‑coupled receptors is involved in neurodegenerative Parkinson's disease
N Nakano, S Matsuda, M Ichimura… - International …, 2017 - spandidos-publications.com
Parkinson's disease (PD) is a common progressive and multifactorial neurodegenerative
disease, characterized by the loss of midbrain dopaminergic neurons. Numerous …
disease, characterized by the loss of midbrain dopaminergic neurons. Numerous …
Inhibition of p38α MAPK restores neuronal p38γ MAPK and ameliorates synaptic degeneration in a mouse model of DLB/PD
Alterations in the p38 mitogen-activated protein kinases (MAPKs) play an important role in
the pathogenesis of dementia with Lewy bodies (DLB) and Parkinson's disease (PD) …
the pathogenesis of dementia with Lewy bodies (DLB) and Parkinson's disease (PD) …
Implications of phosphoinositide 3-kinase-Akt (PI3K-Akt) pathway in the pathogenesis of Alzheimer's disease
Alzheimer's disease (AD) is the foremost type of dementia that afflicts considerable morbidity
and mortality in aged population. Several transcription molecules, pathways, and molecular …
and mortality in aged population. Several transcription molecules, pathways, and molecular …
Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system
K Takeda, H Ichijo - Genes to Cells, 2002 - Wiley Online Library
p38 mitogen‐activated protein kinases (MAPKs), together with extracellular signal‐regulated
kinases (ERKs) and c‐Jun N‐terminal kinases (JNKs), constitute the MAPK family. Multiple …
kinases (ERKs) and c‐Jun N‐terminal kinases (JNKs), constitute the MAPK family. Multiple …
[HTML][HTML] Involvement of p38 MAPK in synaptic function and dysfunction
C Falcicchia, F Tozzi, O Arancio, DM Watterson… - International journal of …, 2020 - mdpi.com
Many studies have revealed a central role of p38 MAPK in neuronal plasticity and the
regulation of long-term changes in synaptic efficacy, such as long-term potentiation (LTP) …
regulation of long-term changes in synaptic efficacy, such as long-term potentiation (LTP) …
[HTML][HTML] The contribution of microglia to neuroinflammation in Parkinson's disease
K Badanjak, S Fixemer, S Smajić, A Skupin… - International Journal of …, 2021 - mdpi.com
With the world's population ageing, the incidence of Parkinson's disease (PD) is on the rise.
In recent years, inflammatory processes have emerged as prominent contributors to the …
In recent years, inflammatory processes have emerged as prominent contributors to the …