Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's …
A Kanthasamy, H Jin, S Mehrotra, R Mishra… - Neurotoxicology, 2010 - Elsevier
Parkinson's disease (PD) is a common neurodegenerative movement disorder
characterized by extensive degeneration of dopaminergic neurons in the nigrostriatal …
characterized by extensive degeneration of dopaminergic neurons in the nigrostriatal …
Targeting p38 MAPK pathway for the treatment of Alzheimer's disease
L Munoz, AJ Ammit - Neuropharmacology, 2010 - Elsevier
Accumulating evidence indicates that p38 mitogen-activated protein kinase (MAPK) could
play more than one role in Alzheimer's disease (AD) pathophysiology and that patients …
play more than one role in Alzheimer's disease (AD) pathophysiology and that patients …
Neuroprotective and therapeutic strategies against Parkinson's disease: recent perspectives
S Sarkar, J Raymick, S Imam - International journal of molecular sciences, 2016 - mdpi.com
Parkinsonism is a progressive motor disease that affects 1.5 million Americans and is the
second most common neurodegenerative disease after Alzheimer's. Typical …
second most common neurodegenerative disease after Alzheimer's. Typical …
Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis
Substantial evidence implicates abnormal protein kinase function in various aspects of
Parkinson's disease (PD) etiology. Elevated phosphorylation of the PD-defining pathological …
Parkinson's disease (PD) etiology. Elevated phosphorylation of the PD-defining pathological …
Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade
K Maiese, ZZ Chong, S Wang, YC Shang - International journal of …, 2012 - mdpi.com
Oxidative stress impacts multiple systems of the body and can lead to some of the most
devastating consequences in the nervous system especially during aging. Both acute and …
devastating consequences in the nervous system especially during aging. Both acute and …
PI3K/AKT signal pathway: a target of natural products in the prevention and treatment of Alzheimer's disease and Parkinson's disease
HZ Long, Y Cheng, ZW Zhou, HY Luo… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD) and Parkinson's disease (PD) are two typical neurodegenerative
diseases that increased with aging. With the emergence of aging population, the health …
diseases that increased with aging. With the emergence of aging population, the health …
Signaling pathways in Parkinson's disease: molecular mechanisms and therapeutic interventions
X Dong-Chen, C Yong, X Yang, ST Chen-Yu… - Signal transduction and …, 2023 - nature.com
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …
worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …
[HTML][HTML] Damage to dopaminergic neurons by oxidative stress in Parkinson's disease
JD Guo, X Zhao, Y Li, GR Li… - … journal of molecular …, 2018 - spandidos-publications.com
Oxidative stress is increasingly recognized as a central event contributing to the
degeneration of dopaminergic neurons in the pathogenesis of Parkinson's disease (PD) …
degeneration of dopaminergic neurons in the pathogenesis of Parkinson's disease (PD) …
Parkinson's disease: a short story of 200 years
L Cuenca, AL Gil Martinez, L Cano Fernandez… - 2019 - digitum.um.es
After Alzheimer's disease, Parkinson's disease (PD) is the second most prevalent and
incidental neurodegenerative disorder, affecting more than 2% of the population older than …
incidental neurodegenerative disorder, affecting more than 2% of the population older than …
The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease
SAL Corrêa, KL Eales - Journal of signal transduction, 2012 - Wiley Online Library
A significant amount of evidence suggests that the p38‐mitogen‐activated protein kinase
(MAPK) signalling cascade plays a crucial role in synaptic plasticity and in …
(MAPK) signalling cascade plays a crucial role in synaptic plasticity and in …