Both Parkinson's disease (PD) and stroke are debilitating conditions that result in neuronal
death and loss of neurological functions. These two conditions predominantly affect aging …

Raf kinase inhibitor protein (RKIP) is a major negative mediator of the extracellular signal-
related kinase (ERK)/mitogen-activated protein kinase (MAPK) pathway. The …

Parkinson's disease (PD) is the second most common multifactorial neurodegenerative
disorder affecting 3% of population during elder age. The loss of substantia nigra, pars …

Neurodegenerative disorders lead to disability and death in a significant proportion of the
world's population. However, many disorders of the nervous system remain with limited …

Parkinson's disease (PD) is one of the most common age‑related neurodegenerative
diseases, which results from a number of environmental and inherited factors. PD is …

Parkinson's disease (PD) is a common neurodegenerative disorder. Neuronal cell death in
PD is still poorly understood, despite a wealth of potential pathogenic mechanisms and …

Inflammation in the central nervous system (CNS) is a common feature of age-related
neurodegenerative diseases. Proinflammatory cytokines, such as IL-1β and TNFα, are …

Existing therapeutic strategies for managing Parkinson disease (PD), which focus on
addressing the loss of dopamine and dopaminergic function linked with degeneration of …

Increasing evidence suggests that c-Jun N-terminal kinase (JNK) is an important kinase
mediating neuronal apoptosis in Parkinson's disease (PD) model induced by 1-methyl-4 …

Parkinson's disease (PD) is the second most common neurodegenerative disorder. It is
characterized by the accumulation of intracellular α-synuclein aggregates and the …