Angiotensin-converting enzyme 2 and COVID-19: patients, comorbidities, and therapies

G Pathangey, PP Fadadu… - American Journal of …, 2021 - journals.physiology.org
On March 11, 2020, the World Health Organization declared coronavirus disease 2019
(COVID-19) a pandemic, and the reality of the situation has finally caught up to the …

Coronavirus disease 2019 (COVID-19) and the renin-angiotensin system: A closer look at angiotensin-converting enzyme 2 (ACE2)

AE Zemlin, OJ Wiese - Annals of clinical biochemistry, 2020 - journals.sagepub.com
Since the first cases of atypical pneumonia linked to the Huanan Seafood Wholesale Market
in Wuhan, China, were described in late December 2019, the global landscape has …

Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

AR Bourgonje, AE Abdulle, W Timens… - The Journal of …, 2020 - Wiley Online Library
Abstract Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional
host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …

COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection

S Beyerstedt, EB Casaro, ÉB Rangel - European journal of clinical …, 2021 - Springer
COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Angiotensin-
converting enzyme 2 (ACE2) is not only an enzyme but also a functional receptor on cell …

Organ‐protective effect of angiotensin‐converting enzyme 2 and its effect on the prognosis of COVID‐19

H Cheng, Y Wang, GQ Wang - Journal of medical virology, 2020 - Wiley Online Library
This article reviews the correlation between angiotensin‐converting enzyme 2 (ACE2) and
severe risk factors for coronavirus disease 2019 (COVID‐19) and the possible mechanisms …

Angiotensin-converting enzyme 2 expression and severity of SARS-CoV-2 infection

S Alabsi, A Dhole, S Hozayen, SA Chapman - Microorganisms, 2023 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2), first discovered in 2000, serves as an important
counterregulatory enzyme to the angiotensin II-mediated vasoconstrictive, pro-inflammatory …

The Impact of Angiotensin-Converting Enzyme 2 (ACE2) Expression Levels in Patients with Comorbidities on COVID-19 Severity: A Comprehensive Review

R Rodrigues, S Costa de Oliveira - Microorganisms, 2021 - mdpi.com
Angiotensin-Converting Enzyme 2 (ACE2) has been proved to be the main host cell receptor
for the binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the …

A comprehensive guide to the pharmacologic regulation of angiotensin converting enzyme 2 (ACE2), the SARS-CoV-2 entry receptor

M Oz, DE Lorke, N Kabbani - Pharmacology & therapeutics, 2021 - Elsevier
The recent emergence of coronavirus disease-2019 (COVID-19) as a global pandemic has
prompted scientists to address an urgent need for defining mechanisms of disease …

Renin-angiotensin system blockers and the COVID-19 pandemic: at present there is no evidence to abandon renin-angiotensin system blockers

AHJ Danser, M Epstein, D Batlle - Hypertension, 2020 - Am Heart Assoc
During the spread of the severe acute respiratory syndrome coronavirus-2, some reports of
data still emerging and in need of full analysis indicate that certain groups of patients are at …

The impact of angiotensin-converting enzyme 2 (ACE2) expression on the incidence and severity of COVID-19 infection

AO Kaseb, YI Mohamed, AE Malek, II Raad… - Pathogens, 2021 - mdpi.com
The novel coronavirus disease 2019 (COVID-19) pandemic has led to an unprecedented
threat to the international community and raised major concerns in terms of public health …