Osteoarthritis (OA) is a multifactorial disease and nutrition is a modifiable factor that may
contribute to disease onset or progression. A detailed understanding of mechanisms …

Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability.
There is no cure for OA, and no effective treatments which arrest or slow its progression …

The natural process of aging gradually causes changes in living organisms, leading to the
deterioration of organs, tissues, and cells. In the case of osteoarthritis (OA), the degradation …

Osteoarthritis (OA) is a disease associated to age or conditions that precipitate aging of
articular cartilage, a post-mitotic tissue that remains functional until the failure of major …

Abstract Forkhead box O3 (FOXO3) transcription factor is involved in chondral homeostasis
of normal, aging and osteoarthritis (OA) cartilage. At present, we aimed to investigate …

Osteoarthritis (OA) is the most common degenerative joint disease characterized by
enzymatic degradation of the cartilage extracellular matrix (ECM) causing joint pain and …

To identify the therapeutic potential for cartilage degradation and its action mechanisms, the
effects of naturally-occurring flavonoids on matrix metalloproteinase-13 (MMP-13) induction …

Abstract Background Achyranthes bidentata Blume (A. bidentata) is a common Chinese
herb used to treat osteoarthritis (OA). Achyranthoside D (Ach-D) is a glucuronide saponin …

Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying
drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major …

At present, an increasing number of individuals are affected by osteoarthritis (OA), resulting
in a heavy socioeconomic burden. OA in knee joints is caused by the release of …