A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles

J Claesen, JB Spagnolo, SF Ramos, KL Kurita… - Science translational …, 2020 - science.org
The composition of the skin microbiota varies widely among individuals when sampled at
the same body site. A key question is which molecular factors determine strain-level …

[HTML][HTML] Identification of a human skin commensal bacterium that selectively kills Cutibacterium acnes

AM O'Neill, T Nakatsuji, A Hayachi, MR Williams… - Journal of Investigative …, 2020 - Elsevier
The microbiome represents a vast resource for drug discovery, as its members engage in
constant conflict to outcompete one another by deploying diverse strategies for survival …

Interference and co-existence of staphylococci and Cutibacterium acnes within the healthy human skin microbiome

CM Ahle, K Stødkilde, A Poehlein, M Bömeke… - Communications …, 2022 - nature.com
Human skin is populated by trillions of microbes collectively called the skin microbiome.
Staphylococcus epidermidis and Cutibacterium acnes are among the most abundant …

What lives on our skin: ecology, genomics and therapeutic opportunities of the skin microbiome

TC Scharschmidt, MA Fischbach - Drug Discovery Today: Disease …, 2013 - Elsevier
Our skin is home to a rich community of microorganisms. Recent advances in sequencing
technology have allowed more accurate enumeration of these human-associated microbiota …

Microbial ecology of the skin in the era of metagenomics and molecular microbiology

GD Hannigan, EA Grice - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
The skin is the primary physical barrier between the body and the external environment and
is also a substrate for the colonization of numerous microbes. Previously, dermatological …

[HTML][HTML] The human skin microbiome

AL Byrd, Y Belkaid, JA Segre - Nature Reviews Microbiology, 2018 - nature.com
Functioning as the exterior interface of the human body with the environment, skin acts as a
physical barrier to prevent the invasion of foreign pathogens while providing a home to the …

Commensal microbiota modulate gene expression in the skin

JS Meisel, G Sfyroera, C Bartow-McKenney, C Gimblet… - Microbiome, 2018 - Springer
Background The skin harbors complex communities of resident microorganisms, yet little is
known of their physiological roles and the molecular mechanisms that mediate cutaneous …

[HTML][HTML] Research techniques made simple: profiling the skin microbiota

MD Grogan, C Bartow-McKenney, L Flowers… - Journal of Investigative …, 2019 - Elsevier
Skin is colonized by microbial communities (microbiota) that participate in immune
homeostasis, development and maintenance of barrier function, and protection from …

The skin microbiome

EA Grice, JA Segre - Nature reviews microbiology, 2011 - nature.com
The skin is the human body's largest organ, colonized by a diverse milieu of
microorganisms, most of which are harmless or even beneficial to their host. Colonization is …

Microbial ecology of the human skin

AM Cundell - Microbial ecology, 2018 - Springer
This review article on the skin microbiota was written in response to recent advances that
transitioned from culture methods to PCR amplification and sequencing of bacterial and …