The FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the
essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell …

FOXO transcription factors, functioning downstream of the PI3K-PTEN-AKT (PKB) signalling
cascade, are essential for cell proliferation, differentiation, DNA damage repair and …

FoxO proteins (FoxOs) are transcription factors with a common DNA binding domain that
confers selectivity for DNA interaction. In human cells, four proteins (FoxO1, FoxO3, FoxO4 …

The FOXO3a and FOXM1 forkhead transcription factors are key players in cancer initiation,
progression, and drug resistance. Recent research shows that FOXM1 is a direct …

Introduction: FOXM1 is one of the most frequently overexpressed proteins in human solid
cancers. Here, we discuss novel direct targets of FOXM1 as well as new pathways involving …

Cancer is one of the major causes of death and a significant obstacle to increasing life
expectancy worldwide. Chemotherapy remains the first-line adjuvant therapeutic option for …

The Forkhead box protein M1 (FOXM1) transcription factor is a regulator of myriad biological
processes, including cell proliferation, cell cycle progression, cell differentiation, DNA …

FOXO transcription factors are important regulators of cell fate decisions, capable of
inducing cell death as well as promoting cell survival and resistance to environmental stress …

Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …

Forkhead box C1 (FOXC1) is an essential member of the forkhead box transcription factors
and has been highlighted as an important transcriptional regulator of crucial proteins …