Endothelial adherens junctions maintain vascular integrity. Arteries and veins differ in their
permeability but whether organization and strength of their adherens junctions vary has not …

Vascular endothelial (VE)-cadherin is the endothelium-specific member of the cadherin
family of homotypic cell adhesion molecules. VE-cadherin, but not the cell adhesion …

Objective: To identify proteins responsible for intercellular junction integrity in human
umbilical vein endothelial cells (HUVEC), we produced a monoclonal antibody that …

Endothelial cells control the passage of plasma constituents and circulating cells from blood
to the underlying tissues. This specialized function is lost or impaired in several pathological …

The regulation of endothelial cell contacts is of central importance for the barrier function of
the blood vessel wall and for the control of leukocyte extravasation. In addition, the plasticity …

Engagement of vascular endothelial (VE)-cadherin leads to the cessation of proliferation
commonly known as' contact inhibition'. We show that VE-cadherin inhibits growth by …

Cell to cell junctions direct endothelial responses both in quiescent and angiogenic vessels.
Endothelial cells express both tight and adherens junctions. Although different in their …

Endothelial cells (ECs) express 2 members of the cadherin family, VE and N-cadherin.
Although VE-cadherin induces EC homotypic adhesion, N-cadherin function in ECs remains …

Vascular endothelial cadherin (VE-cadherin, cadherin-5, or 7B4) is an endothelial specific
cadherin that regulates cell to cell junction organization in this cell type. Cadherin linkage to …

Human vascular endothelial cadherin (VE-cadherin, 7B4/cadherin-5) is an endothelial-
specific cadherin localized at the intercellular junctions. To directly investigate the functional …