Challenges and demand for modeling disorders of consciousness following traumatic brain injury

JC O'Donnell, KD Browne, TJ Kilbaugh, HI Chen… - Neuroscience & …, 2019 - Elsevier
Following severe traumatic brain injury (TBI), many patients experience coma—an
unresponsive state lacking wakefulness or awareness. Coma rarely lasts more than two …

Prognosis and enhancement of recovery in disorders of consciousness

ME Russell, FM Hammond, B Murtaugh - NeuroRehabilitation, 2024 - content.iospress.com
Disorders of consciousness after severe brain injury encompass conditions of coma,
vegetative state/unresponsive wakefulness syndrome, and minimally conscious state. DoC …

The vegetative and minimally conscious states: diagnosis, prognosis and treatment

R Hirschberg, JT Giacino - Neurologic clinics, 2011 - neurologic.theclinics.com
Severe acquired brain injury has profound impact on alertness, cognition, and behavior.
Among those who survive the initial injury, a significant minority fail to fully recover self and …

Research considerations for prospective studies of patients with coma and disorders of consciousness

L Tinti, T Lawson, E Molteni, D Kondziella… - Brain …, 2024 - academic.oup.com
Disorders of consciousness are neurological conditions characterized by impaired arousal
and awareness of self and environment. Behavioural responses are absent or are present …

Thalamic and extrathalamic mechanisms of consciousness after severe brain injury

ES Lutkenhoff, J Chiang, L Tshibanda… - Annals of …, 2015 - Wiley Online Library
Objective What mechanisms underlie the loss and recovery of consciousness after severe
brain injury? We sought to establish, in the largest cohort of patients with disorders of …

Spectrum of catastrophic brain injury: coma and related disorders of consciousness

ME Brogan, JJ Provencio - Journal of critical care, 2014 - Elsevier
A great deal of the difficulty patients' families, and in some cases physicians, experience with
the concept of death by neurological criteria (brain death) has to do with a poor …

Between theory and clinic: the contribution of neuroimaging in the field of consciousness disorders

O Gosseries, C Schnakers, S Laureys - Frontiers in neurology, 2019 - frontiersin.org
Patients surviving severe brain injury either recover quickly from coma or go through
prolonged disorders of consciousness (DOC) such as unresponsive wakefulness syndrome …

Prognosis of patients with altered state of consciousness

MA Bruno, D Ledoux, A Vanhaudenhuyse… - Coma and disorders of …, 2012 - Springer
Progress in intensive care has increased the number of patients surviving severe acute
brain damage. These patients classically progress through different stages before fully or …

SECONDs administration guidelines: a fast tool to assess consciousness in brain-injured patients

LRD Sanz, C Aubinet, H Cassol, O Bodart… - JoVE (Journal of …, 2021 - jove.com
Establishing an accurate diagnosis is crucial for patients with disorders of consciousness
(DoC) following a severe brain injury. The Coma Recovery Scale-Revised (CRS-R) is the …

Brain, behavior, and cognitive interplay in disorders of consciousness: a multiple case study

C Aubinet, L Murphy, MA Bahri, SK Larroque… - Frontiers in …, 2018 - frontiersin.org
Patients with prolonged disorders of consciousness (DoC) after severe brain injury may
present residual behavioral and cognitive functions. Yet the bedside assessment of these …