Critical appraisal of salting-out and its implications for chemical and biological sciences

PK Grover, RL Ryall - Chemical reviews, 2005 - ACS Publications
In simple terms, salting-out describes the precipitation of a less soluble material from a
solution in which it is mixed with other substances. For at least 2 centuries, preparative …

[PDF][PDF] Dissolved urate salts out calcium oxalate in undiluted human urine in vitro: implications for calcium oxalate stone genesis

PK Grover, VR Marshall, RL Ryall - Chemistry & biology, 2003 - cell.com
Hyperuricosuria has long been documented as a predisposing factor to calcium oxalate
(CaOx) stone pathogenesis. However, its mechanism is still without sound scientific …

Urinary inhibitors of calcium oxalate crystallization and their potential role in stone formation

RL Ryall - World journal of urology, 1997 - Springer
Cement containing urine will not set. This has been common knowledge for so long that its
discovery would be impossible to trace, yet its implications for urolithiasis were not fully …

Effect of urate on calcium oxalate crystallization in human urine: evidence for a promotory role of hyperuricosuria in urolithiasis

PK Grover, RL Ryall, VR Marshall - Clinical science, 1990 - portlandpress.com
1. The effect of hyperuricosuria, simulated by increasing the concentration of dissolved
urate, on the crystallization of calcium oxalate in human urine was examined. 2. Twenty …

Urate and calcium oxalate stones: from repute to rhetoric to reality.

PK Grover, RL Ryall - Mineral and electrolyte metabolism, 1994 - europepmc.org
A critical appraisal of the evidence commonly cited to support a link between high urate
excretion and calcium oxalate (CaOx) urinary calculi is presented. Two theories have been …

A method for studying inhibitory activity in whole urine

RL Ryall, CM Hibberd, VR Marshall - Urological Research, 1985 - Springer
A method has been developed for inducing and quantifying calcium oxalate crystallisation in
whole human urine. The propensity of a given urine to induce crystal formation was …

Crystallization inhibitors in the pathophysiology and treatment of nephrolithiasis

M Marangella, C Bagnis, M Bruno, C Vitale… - Urologia …, 2004 - karger.com
It is currently agreed that stone formation in the urinary tract requires supersaturation with
respect to a given solid phase. However, this principle fully applies only to stones other than …

Observations upon calcium oxalate crystallization kinetics in simulated urine

JD Miller, AD Randolph, GW Drach - The Journal of Urology, 1977 - Elsevier
Two major etiologic theories of urinary stones are excessive saturation of urine with
crystallizable substances or defects in inhibitors that allow relative supersaturation to occur …

In vitro effect of lemon and orange juices on calcium oxalate crystallization

S Kulaksızoğlu, M Sofikerim, C Cevik - International Urology and …, 2008 - Springer
Aim In recent years significant progress has been made in identifying and quantitating
physico-chemical processes involved in urinary stone formation. The ability of urine to inhibit …

A hypothesis of calcium stone formation: an interpretation of stone research during the past decades

HG Tiselius - Urological Research, 2011 - Springer
An interpretation of previous and recent observation on calcium salt crystallization and
calcium stone formation provide the basis for formulation of a hypothetical series of events …