Overexpression of RFC3 is correlated with ovarian tumor development and poor prognosis

H Shen, M Cai, S Zhao, H Wang, M Li, S Yao, N Jiang - Tumor Biology, 2014 - Springer
Abstract Replication factor C3 (RFC3) is an oncogene that can potentially predict prognosis
in a variety of human cancers. RFC3 expression in ovarian carcinoma has not yet been …

[HTML][HTML] ShRNA-mediated silencing of the RFC3 gene suppress ovarian tumor cells proliferation

H Shen, J Xu, S Zhao, H Shi, S Yao… - International journal of …, 2015 - ncbi.nlm.nih.gov
Ovarian carcinoma is one of the most common and lethal malignancies in the world.
Replication factor C (RFC) plays an important role in DNA replication, DNA damage repair …

[HTML][HTML] Multifaceted regulation and functions of replication factor C family in human cancers

Y Li, S Gan, L Ren, L Yuan, J Liu, W Wang… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Replication factor C (RFC) family is a complex comprised of the RFC1, RFC2, RFC3, RFC4,
and RFC5 subunits, which acts as a primer recognition factor for DNA polymerase. It is …

Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer

J Xiang, L Fang, Y Luo, Z Yang, Y Liao, J Cui… - Journal of translational …, 2014 - Springer
Background Human replication factor C4 (RFC4) is involved in DNA replication as a clamp
loader and is aberrantly regulated across a range of cancers. The current study aimed to …

Oncogenic Potential of Replication Factor C Subunit 4: Correlations with Tumor Progression and Assessment of Potential Inhibitors

M Alaa Eldeen, F Mamdouh, WK Abdulsahib, RA Eid… - Pharmaceuticals, 2024 - mdpi.com
Replication Factor C Subunit 4 (RFC4), an oncogene implicated in many human cancers,
has yet to be extensively studied in many cancer types to determine its expression patterns …

RFC4 promotes the progression and growth of Oral Tongue squamous cell carcinoma in vivo and vitro

J Zhang, L Wang, X Xie - Journal of clinical laboratory analysis, 2021 - Wiley Online Library
Objective Currently, many studies have found that RFC4 was up‐regulated in various
cancers, and related to the progression and development. While the effects of RFC4 in oral …

Up-regulated RFC2 predicts unfavorable progression in hepatocellular carcinoma

Z Ji, J Li, J Wang - Hereditas, 2021 - Springer
Abstract Background Replication factor C (RFC) is closely related to tumor progression and
metastasis. However, the functional significance of RFC2 in hepatocellular carcinoma …

Integrative Genomics Identified RFC3 As an Amplified Candidate Oncogene in Esophageal Adenocarcinoma

WW Lockwood, KL Thu, L Lin, LA Pikor, R Chari… - Clinical Cancer …, 2012 - AACR
Purpose: Esophageal adenocarcinoma (EAC) is a lethal malignancy that can develop from
the premalignant condition, Barrett's esophagus (BE). Currently, there are no validated …

Expression of RFC2 and PCNA in different gestational trophoblastic diseases

JQ Cui, YF Shi, HJ Zhou - Ai Zheng= Aizheng= Chinese Journal of …, 2004 - europepmc.org
High expression of replication factor C (RFC) mRNA in hydatidiform mole and
choriocarcinoma were detected previously with DNA microarray. Replication factor C …

shRNA-mediated silencing of the RFC3 gene suppresses hepatocellular carcinoma cell proliferation

Z Yao, K Hu, HE Huang, S Xu… - International …, 2015 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignancies
worldwide. Replication factor C (RFC) plays an important role in DNA replication and …