Body mass index and adverse outcomes in elderly patients with atrial fibrillation: the AMADEUS trial

K Senoo, GYH Lip - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Obesity has been associated with increased cardiovascular risk
in atrial fibrillation, but little is known in elderly patients with atrial fibrillation. Methods—Post …

Polypharmacy and the efficacy and safety of rivaroxaban versus warfarin in the prevention of stroke in patients with nonvalvular atrial fibrillation

JP Piccini, AS Hellkamp, JB Washam, RC Becker… - Circulation, 2016 - Am Heart Assoc
Background—Patients with atrial fibrillation (AF) often take multiple medications. Methods
and Results—We examined characteristics and compared adjusted outcomes between …

Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor …

JL Halperin, GJ Hankey, DM Wojdyla, JP Piccini… - Circulation, 2014 - Am Heart Assoc
Background—Nonvalvular atrial fibrillation is common in elderly patients, who face an
elevated risk of stroke but difficulty sustaining warfarin treatment. The oral factor Xa inhibitor …

A multicenter prospective cohort study to investigate the effectiveness and safety of apixaban in Japanese elderly atrial fibrillation patients (J‐ELD AF Registry)

K Okumura, T Yamashita, S Suzuki, M Akao… - Clinical …, 2020 - Wiley Online Library
Background A global, randomized clinical trial indicated the efficacy and safety of apixaban
in stroke prevention in patients with nonvalvular atrial fibrillation (NVAF). However, data in …

Direct comparisons of effectiveness and safety of treatment with Apixaban, Dabigatran and Rivaroxaban in atrial fibrillation

M Jansson, S Själander, V Sjögren, H Renlund… - Thrombosis …, 2020 - Elsevier
Abstract Introduction Direct oral anticoagulants (DOACs) have been proven non-inferior or
superior to warfarin in preventing stroke and systemic embolism, with a lower risk of major …

Safety and effectiveness of appropriately and inappropriately dosed rivaroxaban or apixaban versus warfarin in patients with atrial fibrillation: a cohort study with …

A González-Pérez, L Roberts, P Vora, ME Saez… - BMJ open, 2022 - bmjopen.bmj.com
Objectives To investigate effects of appropriately and inappropriately dosed
apixaban/rivaroxaban versus warfarin on effectiveness and safety outcomes in patients with …

Initial apixaban dosing in patients with atrial fibrillation

A Buchholz, L Ueberham, K Gorczynska… - Clinical …, 2018 - Wiley Online Library
Background Apixaban is a non–vitamin K oral anticoagulant approved for prevention of
stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AF). Current …

Real-world comparison of bleeding risks among non-valvular atrial fibrillation patients prescribed apixaban, dabigatran, or rivaroxaban

PG Tepper, J Mardekian, C Masseria, H Phatak… - PloS one, 2018 - journals.plos.org
Limited real-world data are available regarding the comparative safety of non-vitamin K
antagonist oral anticoagulants (NOACs). The objective of this retrospective claims …

Body mass index is an independent predictor of major bleeding in non-valvular atrial fibrillation patients taking dabigatran

CH Lee, TY Lin, SH Chang, CH Chen, YJ Hsu… - International Journal of …, 2017 - Elsevier
Abstract Background/Objectives Adverse bleeding events happened more frequently among
individuals with, or at risk of, a low body mass index (BMI) than others. Despite increasing …

Multi‐center retrospective study evaluating the efficacy and safety of apixaban versus warfarin for treatment of venous thromboembolism in patients with severe …

A Crouch, TH Ng, D Kelley, T Knight… - … : The Journal of …, 2022 - Wiley Online Library
Abstract Study Objective Direct oral anticoagulants are the standard of care for venous
thromboembolism (VTE) treatment. These agents are recommended regardless of patient …