Animal model to study Klebsiella pneumoniae gastrointestinal colonization and host-to-host transmission

TM Young, AS Bray, RK Nagpal, DL Caudell… - Infection and …, 2020 - Am Soc Microbiol
An important yet poorly understood facet of the life cycle of a successful pathogen is host-to-
host transmission. Hospital-acquired infections (HAI) resulting from the transmission of drug …

[HTML][HTML] Host and microbiota factors that control Klebsiella pneumoniae mucosal colonization in mice

HY Lau, GB Huffnagle, TA Moore - Microbes and infection, 2008 - Elsevier
Klebsiella pneumoniae is both an opportunistic pathogen and a commensal organism. We
have previously reported that K. pneumoniae strain IA565 (KpIA565) is non-pathogenic in a …

[HTML][HTML] From Klebsiella pneumoniae Colonization to Dissemination: An Overview of Studies Implementing Murine Models

L Joseph, T Merciecca, C Forestier, D Balestrino… - Microorganisms, 2021 - mdpi.com
Klebsiella pneumoniae is a Gram-negative pathogen responsible for community-acquired
and nosocomial infections. The strains of this species belong to the opportunistic group …

Klebsiella pneumoniae l-Fucose Metabolism Promotes Gastrointestinal Colonization and Modulates Its Virulence Determinants

AW Hudson, AJ Barnes, AS Bray… - Infection and …, 2022 - Am Soc Microbiol
Colonization of the gastrointestinal (GI) tract by Klebsiella pneumoniae is generally
considered asymptomatic. However, gut colonization allows K. pneumoniae to either …

Klebsiella pneumoniae translocates across the intestinal epithelium via Rho GTPase-and phosphatidylinositol 3-kinase/Akt-dependent cell invasion

CR Hsu, YJ Pan, JY Liu, CT Chen, TL Lin… - Infection and …, 2015 - Am Soc Microbiol
Klebsiella pneumoniae is an important pathogen that causes hospital-acquired septicemia
and is associated with the recent emergence of community-acquired pyogenic liver abscess …

Genetic Requirements for Klebsiella pneumoniae-Induced Liver Abscess in an Oral Infection Model

YC Tu, MC Lu, MK Chiang, SP Huang… - Infection and …, 2009 - Am Soc Microbiol
Klebsiella pneumoniae is the predominant pathogen of primary liver abscess. However, our
knowledge regarding the molecular basis of how K. pneumoniae causes primary infection in …

Identification of Klebsiella pneumoniae virulence determinants using an intranasal infection model

MS Lawlor, J Hsu, PD Rick, VL Miller - Molecular microbiology, 2005 - Wiley Online Library
Klebsiella pneumoniae is a Gram‐negative enterobacterium that has historically been, and
currently remains, a significant cause of human disease. It is a frequent cause of urinary tract …

Molecular epidemiology of colonizing and infecting isolates of Klebsiella pneumoniae

RM Martin, J Cao, S Brisse, V Passet, W Wu, L Zhao… - MSphere, 2016 - Am Soc Microbiol
Klebsiella pneumoniae is among the most common causes of hospital-acquired infections
and has emerged as an urgent threat to public health due to carbapenem antimicrobial …

Genome-wide screening for enteric colonization factors in carbapenem-resistant ST258 Klebsiella pneumoniae

HJ Jung, ER Littmann, R Seok, IM Leiner, Y Taur… - MBio, 2019 - Am Soc Microbiol
ABSTRACT A diverse, antibiotic-naive microbiota prevents highly antibiotic-resistant
microbes, including carbapenem-resistant Klebsiella pneumoniae (CR-Kp), from achieving …

Evidence of sharing of Klebsiella pneumoniae strains between healthy companion animals and cohabiting humans

C Marques, A Belas, C Aboim… - Journal of clinical …, 2019 - Am Soc Microbiol
This study aimed to characterize the fecal colonization and sharing of Klebsiella
pneumoniae strains between companion animals and humans living in close contact. Fecal …