Association of Antibiotic Resistance, Cell Adherence, and Biofilm Production with the Endemicity of Nosocomial Klebsiella pneumoniae

MD Alcántar-Curiel… - BioMed research …, 2018 - Wiley Online Library
Klebsiella pneumoniae is a leading cause of multiple nosocomial infections, some of which
are associated with high mortality. The increasing prevalence of antibiotic‐resistant strains …

Characterization of Klebsiella pneumoniae Type 1 Fimbriae by Detection of Phase Variation during Colonization and Infection and Impact on Virulence

C Struve, M Bojer, KA Krogfelt - Infection and immunity, 2008 - Am Soc Microbiol
Klebsiella pneumoniae is recognized as an important gram-negative opportunistic
pathogen. The ability of bacteria to adhere to host structures is considered essential for the …

Genome watch: Klebsiella pneumoniae: when a colonizer turns bad

MJ Dorman, FL Short - Nature Reviews Microbiology, 2017 - go.gale.com
[illus. 1] Klebsiella pneumoniae is one of the most common causes of hospital-acquired
infections worldwide and, owing to the high prevalence of antibiotic-resistant strains, it has …

Comparative phylogenomics of ESBL-, AmpC- and carbapenemase-producing Klebsiella pneumoniae originating from companion animals and humans

R Garcia-Fierro, A Drapeau, M Dazas… - Journal of …, 2022 - academic.oup.com
Background WHO considers ESBL-and carbapenemase-producing Klebsiella pneumoniae
a major global concern. In animals, ESBL-and carbapenemase-producing K. pneumoniae of …

Identifying virulence determinants of multidrug-resistant Klebsiella pneumoniae in Galleria mellonella

S Bruchmann, T Feltwell, J Parkhill… - Pathogens and …, 2021 - academic.oup.com
Infections caused by Klebsiella pneumoniae are a major public health threat. Extensively
drug-resistant and even pan-resistant strains have been reported. Understanding K …

Identification of Klebsiella pneumoniae Genes Involved in Intestinal Colonization and Adhesion Using Signature-Tagged Mutagenesis

N Maroncle, D Balestrino, C Rich… - Infection and …, 2002 - Am Soc Microbiol
Klebsiella pneumoniae is an opportunistic pathogen responsible for nosocomial infections
that initially colonize the intestinal tract of patients. Signature-tagged mutagenesis was used …

Transposon mutagenesis screen of Klebsiella pneumoniae identifies multiple genes important for resisting antimicrobial activities of neutrophils in mice

MK Paczosa, RJ Silver, AL McCabe, AK Tai… - Infection and …, 2020 - Am Soc Microbiol
Klebsiella pneumoniae is a Gram-negative bacterial pathogen that causes a range of
infections, including pneumonias, urinary tract infections, and septicemia, in otherwise …

Close proximity interactions support transmission of ESBL-K. pneumoniae but not ESBL-E. coli in healthcare settings

A Duval, T Obadia, PY Boëlle, E Fleury… - PLoS computational …, 2019 - journals.plos.org
Antibiotic-resistance of hospital-acquired infections is a major public health issue. The
worldwide emergence and diffusion of extended-spectrum β-lactamase (ESBL)-producing …

Systemic infection facilitates transmission of Pseudomonas aeruginosa in mice

KER Bachta, JP Allen, BH Cheung, CH Chiu… - Nature …, 2020 - nature.com
Health care-associated infections such as Pseudomonas aeruginosa bacteremia pose a
major clinical risk for hospitalized patients. However, these systemic infections are …

The characterization of functions involved in the establishment and maturation of Klebsiella pneumoniae in vitro biofilm reveals dual roles for surface …

D Balestrino, JM Ghigo, N Charbonnel… - Environmental …, 2008 - Wiley Online Library
The ability to form biofilm is seen as an increasingly important colonization strategy among
both pathogenic and environmental Klebsiella pneumoniae strains. The aim of the present …