Objectives Isolated REM sleep without atonia (iRSWA) is regarded as prodromal phase of
REM sleep behavior disorder (RBD) and synucleinopathies. Other factors, however, have …

Mild motor abnormalities can herald the beginning of Parkinson´ s disease but their
diagnostic value is limited by multifactorial ageing‐related influences on motor function. We …

Objective While excessive daytime sleepiness (EDS) can predate the clinical diagnosis of
Parkinson disease (PD), associations with underlying PD pathogenesis are unknown. Our …

Aims Abnormal sleep is a common feature of P arkinson's disease (PD) and prodromal
disorders of sleep are frequent (eg restless legs syndrome and rapid eye movement sleep …

Background. Patients with multiple system atrophy (MSA), similarly to patients with alpha‐
synucleinopathies, can present with different sleep problems. We sought to analyze sleep …

Objective To evaluate changes in the expression of clock genes and melatonin levels in
patients with idiopathic REM sleep behavior disorder (RBD) as a potential early stage of …

Objective To determine if hyposmia in isolated REM sleep behavior disorder (IRBD) predicts
short-term conversion to any α-synucleinopathy and declines with time. Methods Olfaction …

Introduction We sought to analyze the blood pressure (BP) circadian rhythm in Parkinson's
disease (PD), multiple system atrophy (MSA), and pure autonomic failure (PAF) and to …

Abstract Introduction Rapid Eye Movement Sleep Behavior Disorder (RBD) and hyposmia
are common in synucleinopathies and they tend to occur in connection to the prodromal …

Introduction Sleep dysfunction is frequent in Dementia with Lewy Bodies (DLB), but
polysomnographic (PSG) data is scarce. Our objectives were to:(1) compare PSG data …