Development and validation of a high-performance liquid chromatography–mass spectrometry assay for the determination of artemether and its metabolite …

C Souppart, N Gauducheau, N Sandrenan… - … of Chromatography B, 2002 - Elsevier
A sensitive and selective method is described for the determination of artemether and its
active dihydroartemisinin metabolite in human plasma using artemisinin as internal …

Development and validation of a high-performance liquid chromatography/tandem mass spectrometry method for the determination of artemether and its active …

L Huang, AL Jayewardene, X Li, F Marzan… - … of pharmaceutical and …, 2009 - Elsevier
To study the pharmacokinetic profile of artemether in children and in the context of antiviral
drugs for HIV infected patients co-infected with malaria, an LC-MS/MS method was …

Simultaneous determination of artemether and its major metabolite dihydroartemisinin in plasma by gas chromatography–mass spectrometry-selected ion monitoring

SS Mohamed, SA Khalid, SA Ward, TSM Wan… - … of Chromatography B …, 1999 - Elsevier
A sensitive, selective, and reproducible GC–MS–SIM method was developed for
determination of artemether (ARM) and dihydroartemisinin (DHA) in plasma using …

Quantitative analysis of artemether and its metabolite dihydroartemisinin in human plasma by LC with tandem mass spectrometry

B Shi, Y Yu, Z Li, L Zhang, Y Zhong, S Su, S Liang - Chromatographia, 2006 - Springer
We report the development and validation of a high-performance liquid-chromatographic–
tandem mass spectrometric method for determination of artemether (ARM) and its active …

Determination of artemether and its major metabolite, dihydroartemisinin, in plasma using high-performance liquid chromatography with electrochemical detection

J Karbwang, K Na-Bangchang, P Molunto… - … of Chromatography B …, 1997 - Elsevier
A rapid, selective, sensitive and reproducible HPLC with recutive electrochemical detection
for quantitatvie determination of artemether (ART) and its plasma metabolite …

Determination of artemether and its metabolite, dihydroartemisinin, in plasma by high-performance liquid chromatography and electrochemical detection in the …

N Sandrenan, A Sioufi, J Godbillon, C Netter… - … of Chromatography B …, 1997 - Elsevier
An analytical method for the determination of artemether (A) and its metabolite
dihydroartemisinin (DHA) in human plasma has been developed and validated. The method …

Ultra-performance liquid chromatography–tandem mass spectrometric method for the determination of Artemisinin in rat serum and its application in pharmacokinetics

L Li, D Pabbisetty, P Carvalho, MA Avery… - … of Chromatography B, 2008 - Elsevier
A rapid and sensitive ultra-performance liquid chromatography–tandem mass spectrometry
(UPLC-MS/MS) method was developed and validated to quantify artemisinin in rat serum …

[HTML][HTML] Quantification of artemisinin in human plasma using liquid chromatography coupled to tandem mass spectrometry

N Lindegardh, J Tarning, PV Toi, TT Hien… - … of pharmaceutical and …, 2009 - Elsevier
A liquid chromatographic tandem mass spectroscopy method for the quantification of
artemisinin in human heparinised plasma has been developed and validated. The method …

Determination of artemether and dihydroartemisinin in blood plasma by high-performance liquid chromatography for application in clinical pharmacological studies

V Navaratnam, SM Mansor, LK Chin, MN Mordi… - … of Chromatography B …, 1995 - Elsevier
A selective reproducible high-performance liquid chromatographic assay for the
simultaneous quantitative determination of the antimalarial compound artemether (ARM) …

A high‐performance liquid chromatography/tandem mass spectrometry method for the determination of artemisinin in rat plasma

J Xing, H Yan, S Zhang, G Ren… - … Communications in Mass …, 2006 - Wiley Online Library
Artemisinin is a widely used antimalarial drug. To evaluate the pharmacokinetics of
artemisinin in rats, a sensitive and specific liquid chromatography/tandem mass …