Molecular approaches to cervical cancer therapy

LM Alvarez-Salas, JA DiPaolo - Current drug discovery …, 2007 - ingentaconnect.com
Cervical cancer is the second most common malignancy in women worldwide. Two HPV
strains, HPV-16 and 18, occur in the 70% of untreated cancers. Expression of viral …

[PDF][PDF] Development and Future of oligo-based therapies for cervical cancer

W Gu, LN Putral, A Irving, NA McMillan - Curr Opin Mol Ther, 2007 - academia.edu
Cervical cancer is an attractive model in which to test gene-specific therapies because
elimination of the human papillomavirus oncogenes, E6 and E7, results in cancer cell death …

Targeted treatments for cervical cancer: a review

O Peralta-Zaragoza, VH Bermúdez-Morales… - OncoTargets and …, 2012 - Taylor & Francis
Cervical cancer is the second most common cause of cancer death in women worldwide
and the development of new diagnosis, prognostic, and treatment strategies merits special …

Prospects of molecularly-targeted therapies for cervical cancer treatment

A Carlos de Freitas… - Current drug …, 2015 - ingentaconnect.com
Cervical cancer is the third most common cancer among women worldwide and is
responsible for 275.000 deaths each year. The development of cervical cancer has been …

[HTML][HTML] Cervical cancer: development of targeted therapies beyond molecular pathogenesis

J Knoff, B Yang, CF Hung, TC Wu - Current obstetrics and gynecology …, 2014 - Springer
It is well-known that the human papillomavirus (HPV) is the causative agent of cervical
cancer. The integration of HPV genes into the host genome causes the upregulation of E6 …

Cervical cancer and HPV infection: ongoing therapeutic research to counteract the action of E6 and E7 oncoproteins

AM Almeida, JA Queiroz, F Sousa, Â Sousa - Drug discovery today, 2019 - Elsevier
Highlights•Human papillomavirus (HPV) has a primordial role in the development of cervical
cancer.•Therapies currently available for cervical cancer treatment are reviewed.•The …

Mechanisms of cervical cancer

PT Soliman, BM Slomovitz, JK Wolf - Drug Discovery Today: Disease …, 2004 - Elsevier
Cervical cancer continues to be a major worldwide health concern, particularly in
developing countries. In the past few decades, great strides have been made in …

Gene discovery in cervical cancer: towards diagnostic and therapeutic biomarkers

CM Martin, L Kehoe, CO Spillane… - Molecular diagnosis & …, 2007 - Springer
Cervical cancer is a potentially preventable disease; however, it remains the second most
common malignancy in women worldwide. The human papillomavirus (HPV) is the single …

[HTML][HTML] Key molecular events in cervical cancer development

SD Balasubramaniam, V Balakrishnan, CE Oon… - Medicina, 2019 - mdpi.com
Cervical cancer is the fourth most common cancer among women. Infection by high-risk
human papillomavirus (HPV) is the main aetiology for the development of cervical cancer …

Emerging drugs for the treatment of cervical cancer

A Serrano-Olvera, L Cetina, J Coronel… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Worldwide, most cervical cancer (CC) patients require the use of drug therapy
either adjuvant, concurrent with radiation or palliative. Areas covered: This review briefly …