The role of vascular smooth muscle cells in the development of aortic aneurysms and dissections
KB Rombouts, TAR van Merrienboer… - European journal of …, 2022 - Wiley Online Library
Background Aortic aneurysms (AA) are pathological dilations of the aorta, associated with
an overall mortality rate up to 90% in case of rupture. In addition to dilation, the aortic layers …
an overall mortality rate up to 90% in case of rupture. In addition to dilation, the aortic layers …
Vascular smooth muscle cells in aortic aneurysm: from genetics to mechanisms
Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the
second most prevalent aortic disease following atherosclerosis, representing the ninth …
second most prevalent aortic disease following atherosclerosis, representing the ninth …
Abdominal aortic aneurysm formation with a focus on vascular smooth muscle cells
Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …
[HTML][HTML] New insight in aetiopathogenesis of aortic diseases
E Allaire, F Schneider, F Saucy, J Dai… - European Journal of …, 2009 - Elsevier
BACKGROUND: Knowledge in the aetiopathogeny of aortic disease helps to characterise
aortic lesions better and determine the risk of evolution and therapeutic strategies as well …
aortic lesions better and determine the risk of evolution and therapeutic strategies as well …
Vascular smooth muscle cell plasticity and autophagy in dissecting aortic aneurysms
Objective—Recent studies suggested the occurrence of phenotypic switching of vascular
smooth muscle cells (VSMCs) during the development of aortic aneurysm (AA). However …
smooth muscle cells (VSMCs) during the development of aortic aneurysm (AA). However …
Vascular smooth muscle cell apoptosis in abdominal aortic aneurysms
RW Thompson, S Liao, JA Curci - Coronary artery disease, 1997 - journals.lww.com
Apoptosis is a naturally occurring mechanism of cell death that plays an important role in
both normal and pathological remodeling of the vessel wall. Abdominal aortic aneurysms …
both normal and pathological remodeling of the vessel wall. Abdominal aortic aneurysms …
From genetics to response to injury: vascular smooth muscle cells in aneurysms and dissections of the ascending aorta
JB Michel, G Jondeau, DM Milewicz - Cardiovascular research, 2018 - academic.oup.com
Vascular smooth muscle cells (vSMCs) play a crucial role in both the pathogenesis of
Aneurysms and Dissections of the ascending thoracic aorta (TAAD) in humans and in the …
Aneurysms and Dissections of the ascending thoracic aorta (TAAD) in humans and in the …
Genetic and epigenetic mechanisms underlying vascular smooth muscle cell phenotypic modulation in abdominal aortic aneurysm
R Gurung, AM Choong, CC Woo, R Foo… - International journal of …, 2020 - mdpi.com
Abdominal aortic aneurysm (AAA) refers to the localized dilatation of the infra-renal aorta, in
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …
Aortic aneurysms and dissections series
YH Shen, SA LeMaire, NR Webb… - … , and vascular biology, 2020 - Am Heart Assoc
The aortic wall is composed of highly dynamic cell populations and extracellular matrix. In
response to changes in the biomechanical environment, aortic cells and extracellular matrix …
response to changes in the biomechanical environment, aortic cells and extracellular matrix …
Monocytes and macrophages in abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …