Complete avoidance of intraoperative opioids remains questionable, as it does not
necessarily ensure avoidance of postoperative opioids. Multimodal analgesia including …

Opioids are an indispensable part of perioperative pain management of cancer surgeries.
Opioids do have some side effects and abuse potential, and some laboratory data suggest a …

CONCLUSIONS We have shown that a targeted approach including a hospital intervention
is successful in a significant decrease in postoperative opioid prescription and resolution of …

Importance The overprescription of opioids to surgical patients is recognized as an important
factor contributing to the opioid crisis. However, the value of prescribing opioid analgesia …

Background Despite advances in opioid-sparing analgesia, opioid prescribing in breast
surgery remains suboptimal. Besides delayed rehabilitation, excess post-operative opioids …

Background The patient‐relevant minimal important difference for opioid consumption
remains undetermined, despite its frequent use as primary outcome in trials on …

Background Evidence-based perioperative analgesia is an important tactic for reducing
patient exposure to opioids in the perioperative period and potentially preventing new …

Opioid-free anesthesia (OFA) is used in surgery to avoid opioid-related side effects.
However, uncertainty exists in the balance between OFA benefits and risks. We searched for …

Background Excessive opioid prescribing after surgery has contributed to the current opioid
crisis; however, the value of prescribing opioids at surgical discharge remains uncertain. We …

Objective: The objective of this review is to determine the effectiveness of non-opioid
pharmacological adjuncts for decreasing perioperative morphine equivalents and acute …