[HTML][HTML] Metabolic reprogramming of host cells in response to enteroviral infection

ML Cheng, KY Chien, CH Lai, GJ Li, JF Lin, HY Ho - Cells, 2020 - mdpi.com
Enterovirus 71 (EV71) infection is an endemic disease in Southeast Asia and China. We
have previously shown that EV71 virus causes functional changes in mitochondria. It is …

[HTML][HTML] Enterovirus 71 induces mitochondrial reactive oxygen species generation that is required for efficient replication

ML Cheng, SF Weng, CH Kuo, HY Ho - PLoS One, 2014 - journals.plos.org
Redox homeostasis is an important host factor determining the outcome of infectious
disease. Enterovirus 71 (EV71) infection has become an important endemic disease in …

Glucose-6-phosphate dehydrogenase deficiency enhances enterovirus 71 infection

HY Ho, ML Cheng, SF Weng… - Journal of General …, 2008 - microbiologyresearch.org
Variations in the cellular microenvironment affect the host's susceptibility to pathogens.
Using glucose-6-phosphate dehydrogenase (G6PD)-deficient fibroblasts as a model, this …

[HTML][HTML] Enteroviral 2B interacts with VDAC3 to regulate reactive oxygen species generation that is essential to viral replication

ML Cheng, CH Wu, KY Chien, CH Lai, GJ Li, YY Liu… - Viruses, 2022 - mdpi.com
Enterovirus (EV) 71 caused episodes of outbreaks in China and Southeast Asia during the
last few decades. We have previously reported that EV71 induces reactive oxygen species …

[HTML][HTML] Involvement of inducible nitric oxide synthase and mitochondrial dysfunction in the pathogenesis of enterovirus 71 infection

D Dang, C Zhang, R Zhang, W Wu, S Chen, J Ren… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Enterovirus71 (EV71) is recognized as the main causative agent of severe hand,
foot and mouth disease (HFMD). However, the pathogenesis of EV71 infection has not been …

[HTML][HTML] Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model

YR Lee, PS Wang, JR Wang, HS Liu - Journal of biomedical science, 2014 - Springer
Background We previously reported that Enterovirus 71 (EV71) infection activates
autophagy, which promotes viral replication both in vitro and in vivo. In the present study we …

[HTML][HTML] Pathological features of enterovirus 71-associated brain and lung damage in mice based on quantitative proteomic analysis

Y Jin, D Li, T Sun, Y Du, Y Gao, R Ding, W Ji… - Frontiers in …, 2021 - frontiersin.org
The outbreaks of enterovirus 71 (EV71)-associated hand, foot, and mouth disease (HFMD)
have emerged as an emergency of global health due to its association with fatal encephalitis …

Enterovirus 71‐induced autophagy detected in vitro and in vivo promotes viral replication

SC Huang, CL Chang, PS Wang… - Journal of medical …, 2009 - Wiley Online Library
Abstract Enterovirus 71 (EV71) is an important pathogen causing death in children under 5
years old worldwide. However, the underlying pathogenesis remains unclear. This study …

Comparative proteome analyses of host protein expression in response to Enterovirus 71 and Coxsackievirus A16 infections

JJ Lee, JBK Seah, VTK Chow, CL Poh, EL Tan - Journal of proteomics, 2011 - Elsevier
Enterovirus 71 (EV71) and Coxsackievirus A16 (CA16) are the main etiological agents of
Hand, Foot and Mouth Disease (HFMD), a common disease among children and had …

[HTML][HTML] The interplays between autophagy and apoptosis induced by enterovirus 71

X Xi, X Zhang, B Wang, T Wang, J Wang, H Huang… - PloS one, 2013 - journals.plos.org
Background Enterovirus 71 (EV71) is the causative agent of human diseases with distinct
severity, from mild hand, foot and mouth disease to severe neurological syndromes, such as …