[HTML][HTML] Metabolic reprogramming of host cells in response to enteroviral infection
ML Cheng, KY Chien, CH Lai, GJ Li, JF Lin, HY Ho - Cells, 2020 - mdpi.com
Enterovirus 71 (EV71) infection is an endemic disease in Southeast Asia and China. We
have previously shown that EV71 virus causes functional changes in mitochondria. It is …
have previously shown that EV71 virus causes functional changes in mitochondria. It is …
[HTML][HTML] Enterovirus 71 induces mitochondrial reactive oxygen species generation that is required for efficient replication
ML Cheng, SF Weng, CH Kuo, HY Ho - PLoS One, 2014 - journals.plos.org
Redox homeostasis is an important host factor determining the outcome of infectious
disease. Enterovirus 71 (EV71) infection has become an important endemic disease in …
disease. Enterovirus 71 (EV71) infection has become an important endemic disease in …
Glucose-6-phosphate dehydrogenase deficiency enhances enterovirus 71 infection
HY Ho, ML Cheng, SF Weng… - Journal of General …, 2008 - microbiologyresearch.org
Variations in the cellular microenvironment affect the host's susceptibility to pathogens.
Using glucose-6-phosphate dehydrogenase (G6PD)-deficient fibroblasts as a model, this …
Using glucose-6-phosphate dehydrogenase (G6PD)-deficient fibroblasts as a model, this …
[HTML][HTML] Enteroviral 2B interacts with VDAC3 to regulate reactive oxygen species generation that is essential to viral replication
ML Cheng, CH Wu, KY Chien, CH Lai, GJ Li, YY Liu… - Viruses, 2022 - mdpi.com
Enterovirus (EV) 71 caused episodes of outbreaks in China and Southeast Asia during the
last few decades. We have previously reported that EV71 induces reactive oxygen species …
last few decades. We have previously reported that EV71 induces reactive oxygen species …
[HTML][HTML] Involvement of inducible nitric oxide synthase and mitochondrial dysfunction in the pathogenesis of enterovirus 71 infection
D Dang, C Zhang, R Zhang, W Wu, S Chen, J Ren… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Enterovirus71 (EV71) is recognized as the main causative agent of severe hand,
foot and mouth disease (HFMD). However, the pathogenesis of EV71 infection has not been …
foot and mouth disease (HFMD). However, the pathogenesis of EV71 infection has not been …
[HTML][HTML] Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model
Background We previously reported that Enterovirus 71 (EV71) infection activates
autophagy, which promotes viral replication both in vitro and in vivo. In the present study we …
autophagy, which promotes viral replication both in vitro and in vivo. In the present study we …
[HTML][HTML] Pathological features of enterovirus 71-associated brain and lung damage in mice based on quantitative proteomic analysis
Y Jin, D Li, T Sun, Y Du, Y Gao, R Ding, W Ji… - Frontiers in …, 2021 - frontiersin.org
The outbreaks of enterovirus 71 (EV71)-associated hand, foot, and mouth disease (HFMD)
have emerged as an emergency of global health due to its association with fatal encephalitis …
have emerged as an emergency of global health due to its association with fatal encephalitis …
Enterovirus 71‐induced autophagy detected in vitro and in vivo promotes viral replication
SC Huang, CL Chang, PS Wang… - Journal of medical …, 2009 - Wiley Online Library
Abstract Enterovirus 71 (EV71) is an important pathogen causing death in children under 5
years old worldwide. However, the underlying pathogenesis remains unclear. This study …
years old worldwide. However, the underlying pathogenesis remains unclear. This study …
Comparative proteome analyses of host protein expression in response to Enterovirus 71 and Coxsackievirus A16 infections
Enterovirus 71 (EV71) and Coxsackievirus A16 (CA16) are the main etiological agents of
Hand, Foot and Mouth Disease (HFMD), a common disease among children and had …
Hand, Foot and Mouth Disease (HFMD), a common disease among children and had …
[HTML][HTML] The interplays between autophagy and apoptosis induced by enterovirus 71
X Xi, X Zhang, B Wang, T Wang, J Wang, H Huang… - PloS one, 2013 - journals.plos.org
Background Enterovirus 71 (EV71) is the causative agent of human diseases with distinct
severity, from mild hand, foot and mouth disease to severe neurological syndromes, such as …
severity, from mild hand, foot and mouth disease to severe neurological syndromes, such as …