Aims: Apelin and its receptor have emerged as promising targets for the treatment of insulin
resistance. Indeed, peripheral administration of apelin stimulates glucose utilization and …

Apelin is an adipokine secreted by adipocytes. Co-expression of apelin and apelin receptor
(APJ) in adipocytes implies the autocrine regulations of apelin on adipocyte functions …

Aims Apelin is a recently identified adipokine known to improve glucose tolerance and
insulin sensitivity in murine models. This study was dedicated to the proof of concept that …

Objective: Apelin is an adipokine which plays a role in the regulation of glucose
homeostasis and may contribute to the link between increased adipose tissue mass and …

The Apelin/APJ system is involved in a wide range of biological functions. For a long time,
Apelin was thought to be the only ligand for APJ. Recently, a new peptide that acts via APJ …

Background Apelin is an adipokine that plays a role in the regulation of glucose
homeostasis and in obesity. The relationship between apelin serum concentration and …

Abstract Apelin and Elabela (Ela) are peptides encoded by APLN and APELA, respectively,
which act on their receptor APJ and play crucial roles in the body. Recent research has …

Apelin is a bioactive peptide discovered recently that has been proved to be an endogenous
ligand of the APJ receptor. Apelin and APJ are widely distributed in the central nervous …

Apelin, an endogenous ligand for the G protein-coupled receptor APJ, is widely expressed
in various organs. Recent research has indicated that the Apelin/APJ system plays an …

The apelin/apelin receptor (ApelinR) signal transduction pathway exerts essential biological
roles, particularly in the cardiovascular system. Disturbances in the apelin/ApelinR axis are …